DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment si:ch211-207l14.1 and LNP1

DIOPT Version :9

Sequence 1:	XP_021332673.1	Gene:	si:ch211-207l14.1 / 562414	ZFINID:	ZDB-GENE-120215-234	Length:	221	Species:	Danio rerio
Sequence 2:	NP_001078920.1	Gene:	LNP1 / 348801	HGNCID:	28014	Length:	178	Species:	Homo sapiens

Alignment Length:	154	Identity:	35/154 - (22%)
Similarity:	57/154 - (37%)	Gaps:	45/154 - (29%)

- Green bases have known domain annotations that are detailed below.

Zfish    19 EEREDDEEQ-----------GEEEEDEQEEEEPEAERKSSWDIPIPSRSLASRRASLPCPAQLKA 72
            |.::||::.           |....:|.:....|..|         .::.:.|:.|||||..:
Human     2 EHKDDDDDDVSFAKWMSSFWGHSWREEDQRGLRERHR---------LQATSHRKTSLPCPLPV-- 55

Zfish    73 MHLSRTHSAAVIPS----PAVLSHCLQS----SAARPCSRFSHVGKNEDVTHTKSSLYERQPHTI 129
              |.|      |||    |...||..|.    |..|...::|..|..::...:|...:
Human    56 --LPR------IPSSDCHPRRHSHEDQEFRCRSHVRDYRKYSEDGSFKEPLESKGRSH------- 105

Zfish   130 STIPEVHEPLERKARFRSRNVMSM 153
            |.|.:..|..||:..||::...|:
Human   106 SKIEKFSESFERQLCFRTKRSASL 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
si:ch211-207l14.1	XP_021332673.1	RING-H2	160..201	CDD:319362
si:ch211-207l14.1	XP_021332673.1	RING-H2 finger (C3H2C3-type)	160..201	CDD:319362
LNP1	NP_001078920.1	LNP1	11..175	CDD:317779	32/145 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..55		9/35 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..108		4/25 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	147..178
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1320740at2759
OrthoFinder	1	1.000	-	-		FOG0009359
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7097
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010