Protein Alignment SUSD2 and susd2

DIOPT Version :10

• Sequence 1: NP_062547.1
• Gene: SUSD2 / 56241
• HGNCID: 30667
• Length: 822
• Species: Homo sapiens
• Sequence 2: XP_031748710.1
• Gene: susd2 / 105946288
• XenbaseID: XB-GENE-5887491
• Length: 1591
• Species: Xenopus tropicalis
• Alignment Length: 801
• Identity: 428/801 - (53%)
• Similarity: 547/801 - (68%)
• Gaps: 33/801 - (4%)

Human     3 PALLPWALLLLATALGPGPGPTADAQESCSMRCGALDGPCSCHPTCSGLGTCCLDFRDFCLEILP 67
            ||||...:.||...|   |...:.|.||||.:||.....||||.||..|.|||.|:..||:.|.|
 Frog     2 PALLLICIGLLTLTL---PPEVSGASESCSSQCGERLQSCSCHTTCQKLQTCCTDYHQFCISISP 63

Human    68 YSGSMMGGKDFVVRHFKMSSPTDASVICRFKDSIQTLGHVDSSGQVHCVSPLLYESGRIPFTVSL 132
            :||::||||||::.:...|  .::::||||.:...|.|:||::|..||:||||.|:|||..|||.
 Frog    64 HSGTLMGGKDFIILNLTFS--PNSTIICRFNNETNTEGYVDAAGIAHCISPLLLETGRISLTVSQ 126

Human   133 DNGHSFPRAGTWLAVHPNKVSMMEKSELVNETRWQYYGTANTSGNLSLTWHVKSLPTQTITIELW 197
            |.||:|.|:|||||||.:|.|:.|||..::..:||||||...:|.|||.|:.|:||::.|:||:|
 Frog   127 DGGHNFTRSGTWLAVHHSKASVAEKSVQLDSKKWQYYGTPGYNGTLSLIWNAKTLPSENISIEVW 191

Human   198 GYEETGMPYSQEWTAKWSYLYPLATHIPNSGSFTFTPKPAPPSYQRWRVGALRIIDSKNYAGQKD 262
            ||.|||.|||..|.|.|.|||.||...||||:|||||.||...|.:|.||.||||.|....||.:
 Frog   192 GYSETGTPYSDTWRADWKYLYTLAPTYPNSGTFTFTPSPAEAPYNQWDVGMLRIIPSDKPHGQMN 256

Human   263 VQALWTNDHALAWHLSDDFREDPVAWARTQCQAWEELE-DQLPNFLEELPDCPCTLTQARADSGR 326
            |.|:|:..|||||||.:.||.|..|||..:|.:|.:.| :.|||||:|.|||||||.|||||:||
 Frog   257 VHAIWSPVHALAWHLEESFRNDSAAWASDKCISWRDAEINALPNFLKETPDCPCTLDQARADTGR 321

Human   327 FFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGSGQQCCYTADGTQLLTADSSGGSTPDRGHD 391
            :.||||||:|:||||||||||||||||:|||.:|.|||||||.:.|.|:||.||:||||||||||
 Frog   322 YHTDYGCDIEKGSVCTYHPGAVHCVRSIQASPQYASGQQCCYDSTGAQVLTFDSTGGSTPDRGHD 386

Human   392 WGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPDCPRYMQRRPSNDCRNYRPPRLASAFGDPHFV 456
            ||:||:|.|||||..|||:|||::|||||||:.:|..||..|||:|||.|:||:.||.|||||||
 Frog   387 WGSPPYRKPPRVPGFSHWMYDVVTFYYCCLWSDNCQYYMDLRPSSDCRTYKPPKAASGFGDPHFV 451

Human   457 TFDGTNFTFNGRGEYVLLEAALTDLRVQAR------AQPGTMSNG--------------TETRGT 501
            ||||:.:||||:|||.|:.::...|.:|||      .:|.|.:.|              :|....
 Frog   452 TFDGSKYTFNGKGEYTLVSSSHKSLSIQARTKAFTVTKPDTGNFGQINAEIHFDDRADRSEVHAA 516

Human   502 GLTAVAVQEGNSDVVEVRLANRTG-GLEVLLNQEVLSFTEQSWMDLKGMFLSVAAGDRVSIMLAS 565
            ||.:||:||.:|||:|||:.:.:. .||.||||||:||.|||||||.|:|:..|....|::|..|
 Frog   517 GLCSVAMQEDDSDVIEVRVKDGSSHELETLLNQEVISFEEQSWMDLVGVFVYSAISSNVTVMFPS 581

Human   566 GAGLEVSVQGPFLSVSVLLPEKFLTHTHGLLGTLNNDPTDDFTLHSGRVLPPGTSPQELFLFGAN 630
            |||:||..:..||||:||||:.|:..|.||||.:||:|.||||..:|..|||..:|.|||..||:
 Frog   582 GAGIEVRRREDFLSVNVLLPDDFMNQTQGLLGVMNNNPADDFTFRNGTSLPPNATPVELFQLGAD 646

Human   631 WTVHNASSLLTYDSWFLVHNFLYQPKHDPTFEPLFPSETTLNPSLAQEAAKLCGDDHFCNFDVAA 695
            |.|.|.|||.||||..|::|  ...|||.||:|.|..|.  |||  :...:|||||.||.||..|
 Frog   647 WAVTNESSLFTYDSQELINN--SHVKHDHTFQPTFSFEE--NPS--EPLLELCGDDEFCRFDGLA 705

Human   696 TGSLSTGTATRVAHQLHQRRMQSLQPVVSCGWLAPPPNGQKEGNRYLAGSTIYFHCDNGYSLAGA 760
            |..|:...||:::..:|...:::|:|.|||||:|||.||:|.|..|||||.:.|.|:.|:.:.|.
 Frog   706 TYDLNVANATKISFLVHSNLVKNLKPEVSCGWIAPPENGEKIGTTYLAGSVVQFKCNAGFIMNGT 770

Human   761 ETSTCQADGTWSSPTPKCQPG 781
            :..||..|||||....:|..|
 Frog   771 KLRTCLPDGTWSGDAAQCLVG 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SUSD2	NP_062547.1	Somatomedin_B	29..64	CDD:460034	19/34 (56%)
		AMOP	289..429	CDD:461048	98/140 (70%)
		VWD	448..613	CDD:459671	89/185 (48%)
		CCP	725..779	CDD:153056	26/53 (49%)
susd2	XP_031748710.1	Somatomedin_B	25..58	CDD:460034	17/32 (53%)
		AMOP	283..424	CDD:461048	98/140 (70%)
		VWD	443..629	CDD:459671	89/185 (48%)
		CCP	735..788	CDD:153056	26/52 (50%)
		Somatomedin_B	794..827	CDD:460034
		AMOP	1052..1192	CDD:461048
		VWD	1200..1374	CDD:214566
		CCP	1487..1541	CDD:153056