Protein Alignment PROC and CG10232

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 132/545 - (24%)
• Similarity: 206/545 - (37%)
• Gaps: 184/545 - (33%)

Human   118 REC-IEEICDFEEA----KEIFQNVDDTLAFWSKH--VDGDQCLVLPLEHPCASLCCGHGTCIDG 175
            ::| :.|.|...:|    |...|:.|.:   |::.  :...||                     |
  Fly    31 KKCDVNEDCTHLKACPPLKYFLQSADIS---WAREAILRDKQC---------------------G 71

Human   176 IGSFSCDCRSGWEGRF---------CQRGEGERWMLAGGGAGLGPGWGRGTSTSCPR-------- 223
            ..|:.|. :.|:|.|.         |.:..|.:|                ||.....
  Fly    72 YNSYCCR-KEGYERRSNEQCVMLNDCPQFNGRKW----------------TSDILKSIINKICYI 119

Human   224 ---PPLPAEVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKL----GDDLLQ---------CHP 272
               .||.....::||.........|  :|:...|.|| |..||    ..::|.         |.|
  Fly   120 DHFQPLVRRRVYVNCQRQEIFPCQY--DEICRSRDSC-PFLKLKRKKAQNILMSRQCGINTYCCP 181

Human   273 AVKFP-CGRPWK--RMEK-KRSHLKRDTED-------QEDQVDPRLID----------------- 309
            ..:|| |....|  |::| .|.| ....||       ::..:|.|.||
  Fly   182 KQEFPDCPADEKCIRLDKCLRIH-NTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLP 245

Human   310 --------------GKMTRRGDSPWQVVLLDSKKKLA-----CGAVLIHPSWVLTAAHCMDESKK 355
                          |...|..:.||..:|:...::|:     |...||:..:|||||||:.:.|.
  Fly   246 TSCGQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKM 310

Human   356 L-------LVRLGEYDLRRWEKWE---------LDLDIKEVFVHPNY-SKSTTDNDIALLHLAQP 403
            :       .|||||:|:......:         :::.|:...||..| :.|..::||||:.|..|
  Fly   311 VNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTP 375

Human   404 ATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNE- 467
            ...:..|:|||:|...:...  |...|   :.||||..:||..              .|:.||.
  Fly   376 VRYTHEILPICVPKDPIPLH--NHPLQ---IAGWGYTKNREYS--------------QVLLHNTV 421

Human   468 ------CSEVMSNMVSENMLCA-GILGDRQDACEGDSGGPMVASFHGTW----FLVGLVSWG-EG 520
                  |.:.:|...:|:.:|| ||.|  :|:||||||||::.:.:..:    :|.|:||:| |.
  Fly   422 YENRYYCQDKISFFRNESQICASGIRG--EDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSEN 484

Human   521 CGLLHNYGVYTKVSRYLDWIHGHIR 545
            || ....|||||...:..||..:::
  Fly   485 CG-DRKPGVYTKTGAFFSWIKANLK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503	8/36 (22%)
		EGF_CA	162..193	CDD:238011	6/39 (15%)
		FXa_inhibition	235..270	CDD:464251	10/47 (21%)
		Tryp_SPc	308..543	CDD:238113	84/300 (28%)
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	82/267 (31%)