Protein Alignment PROC and CG32374

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_729270.1
• Gene: CG32374 / 38848
• FlyBaseID: FBgn0052374
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 348
• Identity: 86/348 - (24%)
• Similarity: 139/348 - (39%)
• Gaps: 77/348 - (22%)

Human   200 WMLAGGGAGLGPGWGRGTSTSCPRPPLPAEVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLG 264
            |:|..||.  ...|.                   ...:|||  |||.|.|        .|..|..
  Fly    15 WILVVGGQ--SKNWS-------------------GYYVDNG--THYLLYE--------GPRIKPQ 48

Human   265 DDL---LQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLD 326
            ..|   :..:||:                    :..:.:|.:..|:::||..:...:|:|.. |.
  Fly    49 TFLPGNISTNPAI--------------------NALEAQDYLPTRIVNGKKIKCSRAPYQCA-LH 92

Human   327 SKKKLACGAVLIHPSWVLTAAHC-MDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKST 390
            ......||.|:::..|:|||.|| :....:..||.|....||..:..   .:::...|||||:.|
  Fly    93 YNNYFICGCVILNRRWILTAQHCKIGNPGRYTVRAGSTQQRRGGQLR---HVQKTVCHPNYSEYT 154

Human   391 TDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVL 455
            ..||:.::.|..|..:.:.:..:.||.:     ...:..:..|.:|||..|:..:..:|    .|
  Fly   155 MKNDLCMMKLKTPLNVGRCVQKVKLPST-----RTKRFPKCYLASGWGLTSANAQNVQR----YL 210

Human   456 NFIKIPVVPHNECSEVMSN---MVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSW 517
            ..:.:..|...:|.:....   .:.:.|:||  ....:|.|.||||||:|  .:|.  |.|:.|:
  Fly   211 RGVIVCKVSRAKCQQDYRGTGIKIYKQMICA--KRKNRDTCSGDSGGPLV--HNGV--LYGITSF 269

Human   518 GEGCGLLHNYGVYTKVSRYLDWI 540
            |.||......|||..|.:|..||
  Fly   270 GIGCASAKYPGVYVNVLQYTRWI 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251	11/37 (30%)
		Tryp_SPc	308..543	CDD:238113	66/237 (28%)
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	65/237 (27%)