Protein Alignment PROC and zetaTry

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 76/276 - (27%)
• Similarity: 121/276 - (43%)
• Gaps: 65/276 - (23%)

Human   298 DQEDQVDPRLIDGKMTRRGDSPWQVVLL-------DSKKKLACGAVLIHPSWVLTAAHCMDESKK 355
            |::...|.|::.|..|.....|:|:.|.       ::..:..||..:.:.:.::|||||:
  Fly    30 DEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV----- 89

Human   356 LLVRLG----EYDLRRWEKWELDLD-----IKEVFVHPN-YSKSTTDNDIALLHLAQPATLSQ-T 409
                :|    :|.:.....::...|     :||:.:|.. ||.:..:||||:|.:..|..|:. |
  Fly    90 ----IGTVASQYKVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFT 150

Human   410 IVPICLPDSGLAERELNQ--AGQETLVTGW------GYHSSREKEAKRNRTFVLNFIKIPVVPHN 466
            |..|.|        .|.|  .|..:.|:||      ||.|::           |..:.:|:|.:.
  Fly   151 IKAIKL--------ALEQPIEGTVSKVSGWGTTSPGGYSSNQ-----------LLAVDVPIVSNE 196

Human   467 ECSEVMSNM------VSENMLCAGILG-DRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLL 524
            .|.:...:.      ::..|||||..| ...|||:||||||:.....    |.|:||||..|.|.
  Fly   197 LCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALP 257

Human   525 HNYGVYTKVSRYLDWI 540
            :..|||..|:....||
  Fly   258 NYPGVYANVAYLRPWI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	73/266 (27%)
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	72/266 (27%)