Protein Alignment PROC and flz

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 87/269 - (32%)
• Similarity: 129/269 - (47%)
• Gaps: 40/269 - (14%)

Human   289 RSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSK-----KKLACGAVLIHPSWVLTAAH 348
            |.|:|          ..|::.||.:..|..||||::.:|.     .|..||.|||...:|:||||
  Fly  1441 RPHVK----------SGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAH 1495

Human   349 CMDESKKLLVR-LGEYDLR--RWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTI 410
            |.......||. :||:|:.  ...|..:..::|.|.||..|..:|.:||:|||.|..|......|
  Fly  1496 CQPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHI 1560

Human   411 VPICLPDSGLAERELNQAGQETLVTGWG---YHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVM 472
            ||||:|:.     ..:..|:...|||||   |......        ||..:::|::.::.|.|:.
  Fly  1561 VPICMPND-----VADFTGRMATVTGWGRLKYGGGVPS--------VLQEVQVPIIENSVCQEMF 1612

Human   473 -----SNMVSENMLCAGILGDRQDACEGDSGGPMVASF-HGTWFLVGLVSWGEGCGLLHNYGVYT 531
                 :..:..:.||||....::|:||||||||:|... .|.:.|.|.||.|..|...:..|||.
  Fly  1613 HTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYM 1677

Human   532 KVSRYLDWI 540
            :.:.|..|:
  Fly  1678 RTTFYKPWL 1686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	83/250 (33%)
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	83/251 (33%)