Protein Alignment PROC and l(2)k05911

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 94/260 - (36%)
• Similarity: 139/260 - (53%)
• Gaps: 24/260 - (9%)

Human   296 TEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMD-----ESKK 355
            |.|||     |::.|......:.||..||..|.|:. ||..||..|.:||||||:.     :...
  Fly   394 TPDQE-----RIVGGINASPHEFPWIAVLFKSGKQF-CGGSLITNSHILTAAHCVARMTSWDVAA 452

Human   356 LLVRLGEYDL-RRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSG 419
            |...||:|:: ..:|...:...||.:..|..:..||..||:|:|.|::|...::.|.|||||.|.
  Fly   453 LTAHLGDYNIGTDFEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTSP 517

Human   420 LAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNM----VSENM 480
             :::..:.:||...|.|||  |.||...:.:   :|..:.||:..:.||:......    :.|:|
  Fly   518 -SQQSRSYSGQVATVAGWG--SLRENGPQPS---ILQKVDIPIWTNAECARKYGRAAPGGIIESM 576

Human   481 LCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIR 545
            :|||...  :|:|.||||||||.:..|.:..||:||||.|||.....||||:|:..|.||:.:|:
  Fly   577 ICAGQAA--KDSCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWIYKNIK 639

Human   546  545
              Fly   640  639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	88/244 (36%)
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		PTZ00449	<198..>376	CDD:185628
		Tryp_SPc	400..637	CDD:238113	88/245 (36%)