DRSC/TRiP Functional Genomics Resources

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Protein Alignment PROC and CG32808

DIOPT Version :10

Sequence 1:XP_024308771.1 Gene:PROC / 5624 HGNCID:9451 Length:556 Species:Homo sapiens
Sequence 2:NP_726740.1 Gene:CG32808 / 318221 FlyBaseID:FBgn0052808 Length:284 Species:Drosophila melanogaster


Alignment Length:256 Identity:83/256 - (32%)
Similarity:131/256 - (51%) Gaps:18/256 - (7%)


- Green bases have known domain annotations that are detailed below.


Human   304 DPRLIDGKMTRRGDSPWQVVLLDSKK-KLACGAVLIHPSWVLTAAHCMDES--KKLLVRLGEYDL 365
            |.::::|.....|:.|:.|.|..:|. :.:|||.|::|.||||||||:..|  ::|.::.|...|
  Fly    27 DGKIVNGTTAGPGEFPFVVSLRRAKSGRHSCGATLLNPYWVLTAAHCVRGSSPEQLDLQYGSQML 91

Human   366 RRWEKWELDLDIKEVFVHPNYS-KSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAG 429
            .|  .......:..:||||.|. :....||||||.|||...||:.:.|:.||:    .|::....
  Fly    92 AR--NSSQVARVAAIFVHPGYEPEDKYVNDIALLQLAQSVALSKFVQPVRLPE----PRQVTPGN 150

Human   430 QETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACE 494
            ...::.|||.:::.....:.     |..:|:.|....||||.....:.::.:|||:....:..|.
  Fly   151 ASAVLAGWGLNATGGVVQQH-----LQKVKLQVFSDTECSERHQTYLHDSQICAGLPEGGKGQCS 210

Human   495 GDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSW 554
            ||||||::  ..|:...||:|||. :.|......||:|:||.|:|||...:.....|...|
  Fly   211 GDSGGPLL--LIGSDTQVGIVSWSIKPCARPPFPGVFTEVSAYVDWIVETVNSYSPPSSLW 269

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PROCXP_024308771.1 GLA 85..148 CDD:214503
EGF_CA 162..193 CDD:238011
FXa_inhibition 235..270 CDD:464251
Tryp_SPc 308..543 CDD:238113 80/239 (33%)
CG32808NP_726740.1 Tryp_SPc 30..258 CDD:238113 80/240 (33%)
Blue background indicates that the domain is not in the aligned region.

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