Protein Alignment PROC and CG32376

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_729271.1
• Gene: CG32376 / 318002
• FlyBaseID: FBgn0052376
• Length: 291
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 80/311 - (25%)
• Similarity: 142/311 - (45%)
• Gaps: 58/311 - (18%)

Human   238 DNGGCTHYCL----EEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTED 298
            |||  |||.|    |::       ||....|:  :..:|.:                    :..:
  Fly    24 DNG--THYLLYGKPEDI-------APTPNFGN--ISSNPFI--------------------NALE 57

Human   299 QEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHC-MDESKKLLVRLGE 362
            .::....|:::||.....::|:| ..|..:....||.|:|:..|:|||.|| ....:|..||:|.
  Fly    58 AQESFPTRIVNGKRIPCTEAPFQ-GSLHYEGYFVCGCVIINKIWILTAHHCFFGPPEKYTVRVGS 121

Human   363 YDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQ 427
            ...||..:..   .:|::.....|:..|..:|:|::.|..|....:.:.|:.||.:     :..:
  Fly   122 DQQRRGGQLR---HVKKIVALAAYNDYTMRHDLAMMKLKSPVYFGKCVRPVKLPST-----KTTK 178

Human   428 AGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSN---MVSENMLCAGILGDR 489
            ..::.:|:|||..|:..:..:|    .|..::|..:..::|.::...   .:.::|:||.  ...
  Fly   179 FPKKFVVSGWGITSANAQNVQR----YLRRVQIDYIKRSKCQKMYKKAGLKIYKDMICAS--RTN 237

Human   490 QDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWI 540
            :|:|.||||||:.:  .|.  |.|:||||.||...:..|||....||:.||
  Fly   238 KDSCSGDSGGPLTS--RGV--LYGIVSWGIGCANKNYPGVYVNCKRYVPWI 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251	11/35 (31%)
		Tryp_SPc	308..543	CDD:238113	67/237 (28%)
CG32376	NP_729271.1	Tryp_SPc	65..284	CDD:214473	66/237 (28%)