Protein Alignment PROC and CG6048

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_572282.1
• Gene: CG6048 / 31528
• FlyBaseID: FBgn0029827
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 95/285 - (33%)
• Similarity: 128/285 - (44%)
• Gaps: 60/285 - (21%)

Human   289 RSHLKRDTEDQEDQVDP-RLIDGKMTRRGDSPWQVVLLDSKKKL----------ACGAVLIHPSW 342
            |:||...........|| |:|:|.....|.:..||.:   :|.|          .||..||.|.|
  Fly    27 RTHLDTKAIRPRFNADPGRIINGTEASLGATRHQVGI---RKALNDGYFFGTGHLCGGSLIRPGW 88

Human   343 VLTAAHC-MDE---------SKKLLVRLGEYDLRRWEKWE-LDLDIKE-VFVHPNYSKSTTDNDI 395
            ||||||| :|:         .::.:|.:|..|  |:.:.. |...|:| :.....:..||.|.||
  Fly    89 VLTAAHCFVDQIIYDGTFVPKEEFIVVMGNLD--RYNRTNTLTFTIEERIMQLDKFDLSTYDKDI 151

Human   396 ALLHL-AQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGW-----GYHSSREKEAKRNRTFV 454
            |||.| ....|...||.||.|....:.|      |....||||     ||.|.           :
  Fly   152 ALLMLNGTVPTGHPTIRPIALNRFAIPE------GVVCQVTGWGNTEDGYVSD-----------I 199

Human   455 LNFIKIPVVPHNEC--SEVMSNMVSENMLCAGIL--GDRQDACEGDSGGPMVASFHGTWFLVGLV 515
            |..:.:|::....|  ...:.:::...|:|||.|  |:: |||.||||||:|....    |.|:|
  Fly   200 LMTVDVPMISEEHCINDSDLGHLIQPGMICAGYLEVGEK-DACAGDSGGPLVCQSE----LAGVV 259

Human   516 SWGEGCGLLHNYGVYTKVSRYLDWI 540
            |||..|.|....||||:||.|.|||
  Fly   260 SWGIQCALPRLPGVYTEVSYYYDWI 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	89/265 (34%)
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	88/265 (33%)