Protein Alignment PROC and CG18420

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_995715.1
• Gene: CG18420 / 2768924
• FlyBaseID: FBgn0028866
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 86/294 - (29%)
• Similarity: 124/294 - (42%)
• Gaps: 52/294 - (17%)

Human   278 CGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSW 342
            ||        .||.||         :.||:::||:..|..|||...|..|..:..||..||....
  Fly    31 CG--------TRSPLK---------LGPRIVNGKVAVRNSSPWMAFLHTSSNQFICGGTLISRRL 78

Human   343 VLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLS 407
            |||||||...:..::||||||: |:.:.:..:..:...|.|..|..:|..||||||.|.......
  Fly    79 VLTAAHCFIPNTTIVVRLGEYN-RKLKGYREEHQVNRTFQHRFYDPNTHANDIALLRLVSNVVYK 142

Human   408 QTIVPICLPDSGLAERELNQAGQETLVTGWG----YHSSREKEAKRNRTFVLNFIKIPVVPHNEC 468
            ..|.|||:......:..::.....| .||||    .|.|.|          |..:.|...|...|
  Fly   143 ANIRPICIMWDASWKHHIDSIKVLT-GTGWGRTESMHDSSE----------LRTLDISRQPSKMC 196

Human   469 SEVMSNMVSENMLCAGILGDRQDACEGDSGGP---MVASFHGTWFL-VGLVSWGEGCGLLHNYGV 529
            :   ...|..|..|||  ....:.|.||:|||   ||...:...|: ||:....:.|   ....|
  Fly   197 A---FGSVLSNQFCAG--NWNSNLCIGDTGGPVGAMVRYRNAFRFVQVGIAITNKRC---QRPSV 253

Human   530 YTKVSRYLDWI-------HGHIRDKEAPQKSWAP 556
            :|.|..::::|       :|:.|::..|:....|
  Fly   254 FTDVMSHIEFIRRIFLTQNGNDRNQPTPKPDKEP 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	74/249 (30%)
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	74/241 (31%)