Protein Alignment PROC and CG30287

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_726083.1
• Gene: CG30287 / 246530
• FlyBaseID: FBgn0050287
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 292
• Identity: 83/292 - (28%)
• Similarity: 131/292 - (44%)
• Gaps: 72/292 - (24%)

Human   297 EDQEDQVDP------------RLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHC 349
            :.|...:||            |:|:||......:||.|:::: :..:.||..||.|.:|||||||
  Fly    20 QGQPHLLDPQCVTARSEPGLYRVINGKPADLFSNPWMVIIIE-RGMMKCGGSLITPRYVLTAAHC 83

Human   350 MDESK-KLLVRLGEYDLRRWEKWELD------------LDIKEVFVHPNYSKSTTDNDIALLHLA 401
            ..|:| :|.||||:||:.:    .:|            :::...:| |::..:...||||||.|.
  Fly    84 KSETKSQLTVRLGDYDVNQ----AVDCSSYGCIPRPREINVTRTYV-PSHYTNFRKNDIALLRLE 143

Human   402 QPATLSQTIVPICLPDSGLAERELNQAGQETLV----TGWGYHSSREKEAKRNRTFVLNFIKIPV 462
            ........|..|||.   :.:...:....:.||    ||||...||              |..||
  Fly   144 TTVQYGDNIRSICLL---MGDYTWSSNILKNLVKFNTTGWGRTESR--------------INSPV 191

Human   463 -----VPHNE---CSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFH-GT---WFLVGLV 515
                 :.|:.   |::|....:.::.:|  :.......|:||||||:.|... |:   ..|.|:|
  Fly   192 LQQASLTHHHLSYCAQVFGKQLDKSHIC--VASSTGSTCQGDSGGPLTARVRIGSERRVILFGVV 254

Human   516 SWGEGCGLLHNYG--VYTKVSRYLDWIHGHIR 545
            |:    |.:|.:|  |||.|..:.:||..|.:
  Fly   255 SY----GAVHCFGPTVYTNVIHFANWIELHTK 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	78/265 (29%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	78/266 (29%)