Protein Alignment PROC and CG30091

DIOPT Version :10

• Sequence 1: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 76/270 - (28%)
• Similarity: 116/270 - (42%)
• Gaps: 43/270 - (15%)

Human   302 QVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCM--DES-----KKLLVR 359
            |:.|:::.|.......:|| :.|:.:..:..||..:|...:||||||||  ||.     .:|.|.
  Fly    32 QLIPKIVGGVDAGELKNPW-MALIKTNDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQLTVT 95

Human   360 LGEYDL----RRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICL----- 415
            ||.|.|    ......|: .:::.|::|.:::.....||||||.|.:.......|.|:|:
  Fly    96 LGVYHLLATGEHNHPHEI-YNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQ 159

Human   416 --PDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSE 478
              |.:.|.        ||....|||...:.:....      |..:||..:....|..........
  Fly   160 LKPQTDLI--------QEFTAIGWGVTGNGKMSNN------LQMVKIYRIDRKMCEAAFWYTFDY 210

Human   479 NMLCAGILGDRQDACEGDSGGPMVAS--FHG--TWFLVGLVSWG-EGCGLLHNYGVYTKVSRYLD 538
            .|.|||....| |.|:.|||||:...  |.|  ....:|:||.| |.|   ..:|:||.|..::|
  Fly   211 PMFCAGTAVGR-DTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDC---RGFGMYTDVMGHID 271

Human   539 WIHGHIRDKE 548
            :|...:.|.:
  Fly   272 FIERIVLDAD 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	73/257 (28%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	72/256 (28%)
		Tryp_SPc	332..520	CDD:473915