DRSC/TRiP Functional Genomics Resources

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Protein Alignment NSMCE3 and MAGE

DIOPT Version :10

Sequence 1:NP_619649.1 Gene:NSMCE3 / 56160 HGNCID:7677 Length:304 Species:Homo sapiens
Sequence 2:NP_649702.2 Gene:MAGE / 40860 FlyBaseID:FBgn0037481 Length:232 Species:Drosophila melanogaster


Alignment Length:219 Identity:70/219 - (31%)
Similarity:114/219 - (52%) Gaps:17/219 - (7%)


- Green bases have known domain annotations that are detailed below.


Human    68 ARRAQAAPAVGPRSQKQ----LELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDIFPDLFK 128
            :|.|::..|:..:..:|    ::.||..::.::|....:|||||..|::. |.||..    :|.|
  Fly     5 SRAARSQNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIA-VAGDKS----ELKK 64

Human   129 R---AAERLQYVFGYKLVELEPKSNTYILINTLEPVEEDAEMRGDQGTPTTGLLMIVLGLIFMKG 190
            |   ....|...||..|..|:..:.|:| ....|||....|:...| .|...||.|:|..||::|
  Fly    65 RLPLVTNLLAETFGIILTPLDATTKTFI-CTAEEPVASIHELTPAQ-RPQFTLLYIILMYIFLRG 127

Human   191 NTIKETEAWDFLRRLGVYPTKKHLIFG-DPKKLITEDFVRQRYLEYRR--IPHTDPVDYEFQWGP 252
            |.|::::.:..|..|.:||.::|..|| :.:|.|.|.||:|:||:..|  :...|.....|.|||
  Fly   128 NRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGP 192

Human   253 RTNLETSKMKVLKFVAKVHNQDPK 276
            |...|.:..::::|.:|:.||.||
  Fly   193 RAKAEFTFEQMVQFASKLLNQHPK 216

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NSMCE3NP_619649.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..82 3/13 (23%)
Interaction with NSMCE1 78..304 67/209 (32%)
MAGE 92..261 CDD:426270 58/174 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 285..304
MAGENP_649702.2 MAGE 30..201 CDD:426270 59/177 (33%)
Blue background indicates that the domain is not in the aligned region.

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