Protein Alignment TEX14 and btk

DIOPT Version :9

• Sequence 1: XP_011523331.1
• Gene: TEX14 / 56155
• HGNCID: 11737
• Length: 1532
• Species: Homo sapiens
• Sequence 2: XP_021336920.1
• Gene: btk / 568653
• ZFINID: ZDB-GENE-070531-1
• Length: 640
• Species: Danio rerio
• Alignment Length: 513
• Identity: 115/513 - (22%)
• Similarity: 199/513 - (38%)
• Gaps: 117/513 - (22%)

Human    18 LRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDP 82
            ||.|. |..|.| :...|:.|.|....|..|:       .:...|.||.||.|:     |:....
Zfish   213 LRKDE-EYTLLE-ISDPNWFKAKDKYGKEGYI-------PSNYIVQALNGLEKY-----DWYCKN 263

Human    83 NHRC----------FDGSTPVH-AAAFSGNQWILSKLLDAGGDLRLHDERGQNPKTWALTAGKER 136
            .:|.          .||...|. :..|:| ::.:|....|||:                |:|..|
Zfish   264 INRSQAENLLKTENKDGGFLVRDSGKFTG-KYTVSVFTKAGGE----------------TSGSCR 311

Human   137 STQIVEFMQRCASHMQAIIQGFSYDLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVIS 201
            ...|:         :.|..|.:..:.....:.|:.:.|.        |.|..|..:||.......
Zfish   312 HYNIL---------LTADGQFYLAEKHNFTNIPELINYH--------QHNAAGLVSRLKYIVSNR 359

Human   202 AQN---IYSFGFGKFYLTGATQMAYLGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNGSR 263
            |||   ....|:|.:.: ...|:.::..|. .|:..|::      :..:.|.:.|...:|..||
Zfish   360 AQNAPCTAGLGYGSWEI-DPRQLTFIRELG-NGQFGVVK------YGKWQGRHDVAIKMVKEGS- 415

Human   264 VTVKELNLPTHPHCSRLRLADLLIAEQEHSSKLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTL 328
              :.|               |..|.|.:...||.|..|:||..||..|  ....:|.|.:..|.|
Zfish   416 --MSE---------------DDFIEEAKVMMKLCHGNLVQLYGVCTKQ--RPIYIVTEYLANGCL 461

Human   329 FSVLHE---RRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNL- 389
            .:.|.|   ..:...:|.|      ...:|:.::||....||||.|::....:.|.|..::|:.
Zfish   462 LNYLQEGLLNPTSIALLEM------CKDVSEGMKYLEANQFIHRDLAARNCLVDSNGTIKVTDFG 520

Human   390 --EYMLESE---DRGVQRDLTRVPLPTQLYNWAAPEVILQKAATVKSDIYSFSMIMQEILTDD-I 448
              .|:|:.|   ..|     ::.|:     .|:.|||:|....:.||||::|.::|.||.|.. :
Zfish   521 LSRYVLDDEYTSSVG-----SKFPV-----RWSPPEVLLYCKFSSKSDIWAFGVLMWEIYTQGRM 575

Human   449 PWKGLDGSVVKKAVVSGNYLEADVRLPKPYYDIVKSGIHVKQKDRTMNLQDIRYILKN 506
            |:...:.:.:.:.:.:|:.|.......:..:.|:.|..| ::.|.....|::..::|:
Zfish   576 PYDRWNNTEIVEKISAGHRLYRPQMANENVFAIMNSCWH-ERPDERPTFQELVGVIKD 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TEX14	XP_011523331.1	ANK	27..125	CDD:238125	24/108 (22%)
		Ank_2	27..119	CDD:289560	24/102 (24%)
		ANK repeat	27..53	CDD:293786	7/25 (28%)
		ANK repeat	55..86	CDD:293786	7/30 (23%)
		ANK repeat	88..119	CDD:293786	9/31 (29%)
		ANK repeat	121..148	CDD:293786	4/26 (15%)
		PK_SCY1_like	175..507	CDD:270913	79/345 (23%)
btk	XP_021336920.1	PH_Btk	6..145	CDD:269944
		SH3	195..249	CDD:327375	11/44 (25%)
		SH2	252..357	CDD:326550	27/143 (19%)
		PKc_like	376..630	CDD:328722	68/298 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910