Protein Alignment PRKX and Prkx

DIOPT Version :9

• Sequence 1: NP_005035.1
• Gene: PRKX / 5613
• HGNCID: 9441
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_001029135.1
• Gene: Prkx / 501563
• RGDID: 1564076
• Length: 358
• Species: Rattus norvegicus
• Alignment Length: 365
• Identity: 276/365 - (75%)
• Similarity: 306/365 - (83%)
• Gaps: 14/365 - (3%)

Human     1 MEAPGLAQAAAAESDSR-------KVAEETPDGAPALCPSPEALSPEPPVYSLQDFDTLATVGTG 58
            ||.|..|:||..:..:|       |::      |||..|.|.. |.:...:||||:||:||||||
  Rat     1 MEPPACAEAAVKDPAARDHDPVDAKIS------APAADPLPRT-SSQKEGHSLQDWDTIATVGTG 58

Human    59 TFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLY 123
            |||||:||||||.:.:.|||:|||||||||||||||.|||:||||::|||||:|.||.||.||||
  Rat    59 TFGRVNLVKEKTGRRYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTDHDNRFLY 123

Human   124 MLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKL 188
            ||||:|||||||:||||||||||...:||:.||:|||||||||||||||||||||||||:|||||
  Rat   124 MLMEFVPGGELFTYLRNRGRFSSVAAIFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKL 188

Human   189 TDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIY 253
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   189 TDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIY 253

Human   254 QKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKP 318
            |||||.||||||.|||..|||||||||||||||||||||||.|:|.|||||.|:||:||||||||
  Rat   254 QKILACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLKP 318

Human   319 PIVPKIAGDGDTSNFETYPENDWDTAAPVPQKDLEIFKNF 358
            |||||::.|||.||||||||.:.|....|..:|||.||||
  Rat   319 PIVPKLSSDGDISNFETYPEGELDKTPSVSDEDLETFKNF 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKX	NP_005035.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		12/39 (31%)
		PTZ00263	39..358	CDD:140289	260/318 (82%)
		STKc_PRKX_like	47..338	CDD:270763	249/290 (86%)
Prkx	NP_001029135.1	PTZ00263	35..358	CDD:140289	262/323 (81%)
		STKc_PRKX_like	47..338	CDD:270763	249/290 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83693110
Domainoid	1	1.000	465	1.000	Domainoid score	I8414
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55868
Inparanoid	1	1.050	564	1.000	Inparanoid score	I10706
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D119432at9347
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	1	1.000	-	-		oto136822
orthoMCL	1	0.900	-	-		OOG6_100326
Panther	1	1.100	-	-	LDO	PTHR24353
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4144
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	15.400