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Protein Alignment MAP2K1 and Dsor1

DIOPT Version :9

Sequence 1:	NP_002746.1	Gene:	MAP2K1 / 5604	HGNCID:	6840	Length:	393	Species:	Homo sapiens
Sequence 2:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	243/381 - (63%)
Similarity:	298/381 - (78%)	Gaps:	23/381 - (6%)

- Green bases have known domain annotations that are detailed below.

Human    13 PAPDGSAVNGTSS------AETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKI 71
            |.|.....:||.:      .:|:::||.:.||.|::.:.:|||::.||:||:|:|||.|:|.||:
  Fly    26 PTPPFKTPSGTDTHSLLGKPKTSIDALTETLEGLDMGDTERKRIKMFLSQKEKIGELSDEDLEKL 90

Human    72 SELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSD 136
            .|||:||||||.||.|..:.|:|||||||||:||||:.||:|||:||||||.|:|||||||||||
  Fly    91 GELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFPHIVGFYGAFYSD 155

Human   137 GEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSR 201
            ||||||||:|||||||.:||:||||||.|||::::||:|||:|||:.|.|:|||||||||||||.
  Fly   156 GEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSS 220

Human   202 GEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPP 266
            ||||:||||||||||||||||||||||||||||||||||||||||||:||||||||:|.||||||
  Fly   221 GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPP 285

Human   267 DAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFS 331
            :...||.:|     .|.||...:|           .|....||||||||||||||||||...:||
  Fly   286 NTATLESIF-----ADNAEESGQP-----------TDEPRAMAIFELLDYIVNEPPPKLEHKIFS 334

Human   332 LEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTP 387
            .||:|||:.||.|.|.||||||.|:.|.:|::::.||||.:||:|.|:.| .||||
  Fly   335 TEFKDFVDICLKKQPDERADLKTLLSHPWIRKAELEEVDISGWVCKTMDL-PPSTP 389

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.