Protein Alignment MAPK13 and CkIIalpha

DIOPT Version :10

• Sequence 1: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_524918.1
• Gene: CkIIalpha / 48448
• FlyBaseID: FBgn0264492
• Length: 336
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 100/325 - (30%)
• Similarity: 170/325 - (52%)
• Gaps: 40/325 - (12%)

Human    19 WELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQ-HE 82
            |.....|.....:|.|.|..|..||:..:.||..:|.| :|.:.    |:..||:.:|:::: ..
  Fly    31 WGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKIL-KPVKK----KKIKREIKILENLRGGT 90

Human    83 NVIGLLDVF------TPASSLRNFYDFYLVMPFM-QTDLQKIMGMEFSEEKIQYLVYQMLKGLKY 140
            |:|.||.|.      |||          |:...: .||.:::. ...::.:|:|.::::||.|.|
  Fly    91 NIITLLAVVKDPVSRTPA----------LIFEHVNNTDFKQLY-QTLTDYEIRYYLFELLKALDY 144

Human   141 IHSAGVVHRDLKPGNLAV-NEDCELKILDFGLAR--HADAEMTGYVVTRWYRAPEVILSWMHYNQ 202
            .||.|::|||:||.|:.: :|:.:|:::|:|||.  |...|....|.:|:::.||:::.:..|:.
  Fly   145 CHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDY 209

Human   203 TVDIWSVGCIMAEMLTGK-TLFKGKDYLDQLTQILKVTGVPGTE----FVQKLNDKAAKSYIQSL 262
            ::|:||:||::|.|:..| ..|.|.|..|||.:|.||.   |||    ::.|.|......:...|
  Fly   210 SLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVL---GTEELYAYLDKYNIDLDPRFHDIL 271

Human   263 PQTPRKDFTQLFPR-----ASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQ 322
            .:..||.:.:....     .||:|.|.|:|:|..|...||||.:|:.||:|.|..:.:.....||
  Fly   272 QRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVNGQMNPNNQQ 336

Human   323  322
              Fly   337  336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	100/325 (31%)
		TXY	180..182		0/1 (0%)
CkIIalpha	NP_524918.1	STKc_CK2_alpha	18..322	CDD:271034	96/309 (31%)