Protein Alignment MAPK13 and p38b

DIOPT Version :9

• Sequence 1: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 349
• Identity: 204/349 - (58%)
• Similarity: 263/349 - (75%)
• Gaps: 5/349 - (1%)

Human     9 FYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYREL 73
            |||.|:|:|.||:|:||.:...||.||||.||.|:.:.:..|||||||:|||||.:.|||.||||
  Fly     8 FYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYREL 72

Human    74 LLLKHMQHENVIGLLDVF---TPASSLRNFYDFYLVMPFMQTDLQKIM-GMEFSEEKIQYLVYQM 134
            .|||||.|||||||||||   .||.||..|...|:|...|..||..|: ..:.|::.:|:||||:
  Fly    73 RLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQI 137

Human   135 LKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMH 199
            |:||||||||||:||||||.|:||||||||:||||||||.|::||||||.||||||||::|:|||
  Fly   138 LRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMH 202

Human   200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQ 264
            ||||.|||||||||||:|||:|||.|.|::.||..|::|.|.|..||:.:::.::|::||:|||.
  Fly   203 YNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPV 267

Human   265 TPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLE 329
            .||::|..:|..|:|.|.||||||||||.|||:||.|||.||:.|.:.||.:|..|.. :|.|.|
  Fly   268 MPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAAL-YDQSFE 331

Human   330 HEKLTVDEWKQHIYKEIVNFSPIA 353
            ..:|.|::|::.::.|:..|.|.|
  Fly   332 ENELPVEKWREMVFSEVTAFKPTA 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	202/345 (59%)
		TXY	180..182		1/1 (100%)
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	202/345 (59%)
		S_TKc	24..311	CDD:214567	179/286 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.880