Protein Alignment MAPK13 and rl

DIOPT Version :9

• Sequence 1: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 148/338 - (43%)
• Similarity: 220/338 - (65%)
• Gaps: 9/338 - (2%)

Human    19 WELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHEN 83
            :|:...|:...::|.||||.|.||.|..:.::|||||:| ||:.:.:.:|..||:.:|...:|||
  Fly    32 FEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITILTRFKHEN 95

Human    84 VIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGME-FSEEKIQYLVYQMLKGLKYIHSAGVV 147
            :|.:.|:.. ..|:....|.|:|...|:|||.|::..: .|.:.|.|.:||:|:||||||||.|:
  Fly    96 IIDIRDILR-VDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVL 159

Human   148 HRDLKPGNLAVNEDCELKILDFGLARHADAE------MTGYVVTRWYRAPEVILSWMHYNQTVDI 206
            ||||||.||.:|:.|:|||.||||||.||.|      :|.||.||||||||::|:...|.:::||
  Fly   160 HRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDI 224

Human   207 WSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFT 271
            ||||||:||||:.:.:|.||.|||||..||.|.|.|..:.::.:.::.|::|::|||..|...:.
  Fly   225 WSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPWA 289

Human   272 QLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVD 336
            :|||.|...|.|||.|||..:..||:...:||.||:.|.:.||.:|..|:.||..::|::.::.|
  Fly   290 KLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDDISRD 354

Human   337 EWKQHIYKEIVNF 349
            ..|..|::|.:.|
  Fly   355 ALKSLIFEETLKF 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	148/338 (44%)
		TXY	180..182		1/1 (100%)
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	147/335 (44%)
		S_TKc	38..326	CDD:214567	134/289 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810