Protein Alignment MAPK13 and Cdk7

DIOPT Version :10

• Sequence 1: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 299
• Identity: 108/299 - (36%)
• Similarity: 165/299 - (55%)
• Gaps: 30/299 - (10%)

Human    25 YVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIG 86
            |...:.:|.|.:.:|..|.|..:.:.||:||:   ||....:...:.|.||:.:|:.:||||:||
  Fly    12 YAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIG 76

Human    87 LLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM---GMEFSEEKIQYLVYQMLKGLKYIHSAGVVH 148
            |:|||...|::.      ||..||.|||:.|:   .:..::..|:......||||:|:|...::|
  Fly    77 LVDVFGQLSNVS------LVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILH 135

Human   149 RDLKPGNLAVNEDCELKILDFGLARHADAE---MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVG 210
            |||||.||.||.|..|||.|||||:...:.   .|.:|||||||:||::.....|...||:|:||
  Fly   136 RDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVG 200

Human   211 CIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTE----FVQKLNDKAAKSYIQ--SLPQTPRKD 269
            ||:||::.......|...|||||:|....|.| ||    .:.||:|     |:|  :.|.||
  Fly   201 CILAELMLRVPFMPGDSDLDQLTRIFSTLGTP-TEAEWPHLSKLHD-----YLQFRNFPGTP--- 256

Human   270 FTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFF 308
            ...:|..|......|::::..::..:|::..:||:.|:|
  Fly   257 LDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	108/299 (36%)
		TXY	180..182		1/1 (100%)
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	108/299 (36%)