Protein Alignment MAPK13 and p38c

DIOPT Version :10

• Sequence 1: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_996277.1
• Gene: p38c / 2768679
• FlyBaseID: FBgn0267339
• Length: 356
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 146/346 - (42%)
• Similarity: 216/346 - (62%)
• Gaps: 3/346 - (0%)

Human     9 FYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYREL 73
            |.:..:|::.||.|..|.....:|.|::|.|.....:.:....|:|:|.|||:.|..||..|||:
  Fly     4 FVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREI 68

Human    74 LLLKHMQHENVIGLLDVF-TPASSLRNFYDFYLVMPFMQTDLQKI-MGMEFSEEKIQYLVYQMLK 136
            .|||||.|.|||.||:|| .||.::..|...|||...|..||.:. .....|:::|:.::||:|:
  Fly    69 RLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILR 133

Human   137 GLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMHYN 201
            |||||||||||||||||.|:|||.:.|::||||||:|....:||.:|.|.||.|||:|.....|.
  Fly   134 GLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYT 198

Human   202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTP 266
            :.:|:||||||:||::|.:.||:|::|:.|:..::.:.|.|..||:..::.:.:::|::..|...
  Fly   199 KAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQ 263

Human   267 RKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQP-FDDSLEH 330
            |.||..||.....||.||:|||||:..:||:|||:|:.||:.....:|....|...| :|.:.|:
  Fly   264 RCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNFEN 328

Human   331 EKLTVDEWKQHIYKEIVNFSP 351
            ..|.|..||:.:..||.||.|
  Fly   329 MVLPVKCWKELVSHEIRNFRP 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	145/344 (42%)
		TXY	180..182		1/1 (100%)
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	145/344 (42%)