Protein Alignment hsp70l and Hsc70-3

DIOPT Version :10

• Sequence 1: NP_001107061.1
• Gene: hsp70l / 560210
• ZFINID: ZDB-GENE-050321-1
• Length: 643
• Species: Danio rerio
• Sequence 2: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Alignment Length: 631
• Identity: 396/631 - (62%)
• Similarity: 498/631 - (78%)
• Gaps: 15/631 - (2%)

Zfish     6 GIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNTV 69
            |..||||||||||||||:::|:|||||||||||.|||||||| |.|||||||||||:..||.|||
  Fly    29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93

Zfish    70 FDAKRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAE 134
            |||||||||.:.|..||.|:|.:.||||....||.::|:.....|.|.|||||:|||.||||.||
  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAE 158

Zfish   135 AYLGQKVTNAVITVPAYFNDSQRRATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLI 199
            ||||:|||:||:||||||||:||:|||||||||||.|:||||||||||||||||| |..|:|||:
  Fly   159 AYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDK-KEGEKNVLV 222

Zfish   200 FDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRR 264
            |||||||||||:|||::|:|||.||.|||||||||||.|:::||::.:|:|..|||.::.||:::
  Fly   223 FDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQK 287

Zfish   265 LRTACERAKRTLSPSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMD 329
            ||...|:|||.||.|.|..|||:|.:||.||..::|||:||||..||||.||.||:|.|.||.|:
  Fly   288 LRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMN 352

Zfish   330 KAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQD-- 392
            |..:|:||||||||||||:|:|::|||.|:|.::.|||||||||||||||.:|.|:     ||
  Fly   353 KKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGE-----QDTD 412

Zfish   393 -LLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNN 456
             ::||||.||::||||.|||||.||.|||.||||::|.|:|.||||..|.|||:||||.|||||:
  Fly   413 AIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNH 477

Zfish   457 LLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNRITITNDKGRLSKEEIERMV 521
            |||||:||||||||||:|||||:|:|||||||.|||.||.||.:.:|.||||:.||:.|:|:||:
  Fly   478 LLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMI 542

Zfish   522 QEADKYKAEDDLQREKISAKNSLESYAFNMKNSVED-DNLKGKISEEDKKRVVEKCNEAVSWLEN 585
            ::|:|:..||...:|::.::|.|||||:::||.:.| |.|..|:|:::|.::....:|::.|||.
  Fly   543 RDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQ 607

Zfish   586 NQLADKEEYEHQLKELEKVCNPVISKLYQGG----MPAGGCGAQAR 627
            |..||.|||:.|.|:||.:..|||:|||||.    .|.||..|..:
  Fly   608 NPDADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAPPPEGGDDADLK 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hsp70l	NP_001107061.1	PTZ00009	5..643	CDD:240227	396/631 (63%)
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	391/616 (63%)