Protein Alignment MAPK10 and spk1

DIOPT Version :9

• Sequence 1: NP_001304998.1
• Gene: MAPK10 / 5602
• HGNCID: 6872
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_594009.1
• Gene: spk1 / 2542474
• PomBaseID: SPAC31G5.09c
• Length: 372
• Species: Schizosaccharomyces pombe
• Alignment Length: 371
• Identity: 138/371 - (37%)
• Similarity: 215/371 - (57%)
• Gaps: 25/371 - (6%)

Human    38 NMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQ 102
            |.:|..|... .|....|..|.:.:.|:.:..||.||.|:||||........||:||: .||.:.
pombe    14 NSNKESVATS-RSPHTHDLNFELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKI-HPFNHP 76

Human   103 THAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDHERM 166
            ....|..||:.|::...|:||||:|::. |..:.:|.:|||:|.|||:.:|.:||:.: |..:..
pombe    77 VFCLRTLREIKLLRHFRHENIISILDIL-PPPSYQELEDVYIVQELMETDLYRVIRSQPLSDDHC 140

Human   167 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART----AGTSFMMTPYVVTR 227
            .|..||:|..:|.:||||::||||||||:::.::|.||:.||||||:    .|....||.||.||
pombe   141 QYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATR 205

Human   228 YYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTP-CPEFMKKL 290
            :|||||::|.. .|.:.:|:||.|||:.||:..:.||||:||..|...::..|||| ..:|.:..
pombe   206 WYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIK 270

Human   291 QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQ 355
            ....|.|:::.|....::|..|||.:            :..|.|||.|:|..:|.|||:.::||:
pombe   271 SARARKYIKSLPFTPKVSFKALFPQA------------SPDAIDLLEKLLTFNPDKRITAEEALK 323

Human   356 HPYINVWYDPAE--VEAP-PPQIYDKQLDEREHTIEEWKELIYKEV 398
            |||:..::|.::  ..:| ||.:.|...::.:..|...|.||::||
pombe   324 HPYVAAYHDASDEPTASPMPPNLVDLYCNKEDLEIPVLKALIFREV 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK10	NP_001304998.1	STKc_JNK	63..398	CDD:270840	130/344 (38%)
		S_TKc	64..359	CDD:214567	120/301 (40%)
spk1	NP_594009.1	STKc_ERK1_2_like	33..371	CDD:270839	133/351 (38%)
		S_TKc	39..327	CDD:214567	120/301 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910