Protein Alignment MAPK10 and sty1

DIOPT Version :9

• Sequence 1: NP_001304998.1
• Gene: MAPK10 / 5602
• HGNCID: 6872
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_592843.1
• Gene: sty1 / 2541652
• PomBaseID: SPAC24B11.06c
• Length: 349
• Species: Schizosaccharomyces pombe
• Alignment Length: 358
• Identity: 152/358 - (42%)
• Similarity: 224/358 - (62%)
• Gaps: 25/358 - (6%)

Human    47 QFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRE 111
            :|...::..:.|.:..||.:|:|||.||.|:||:|.|.:...|||:||:.:||.....|||.|||
pombe     3 EFIRTQIFGTCFEITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRE 67

Human   112 LVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-QMELDHERMSYLLYQMLC 175
            |.|:|.:.|:|||||.::|     :..|:|:|.|.||:..:|.::: ...|:.:.:.|.|||:|.
pombe    68 LKLLKHLRHENIISLSDIF-----ISPFEDIYFVTELLGTDLHRLLTSRPLETQFIQYFLYQILR 127

Human   176 GIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL-GMG 239
            |:|.:||||:||||||||||::..:|.|||.||||||....  .||.||.||||||||::| ...
pombe   128 GLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQK 190

Human   240 YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL--QPTVRNYVENRP 302
            |...|||||.|||..||:..|.||||||:::|::.:.|.||||..|.::.:  :.|:| :|::.|
pombe   191 YNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICSKNTLR-FVQSLP 254

Human   303 KYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAE 367
            :...:.|.:.|.:    ||.:        |.|||.||||.||.||||..|||.|.|:..::||.:
pombe   255 QKEKVPFAEKFKN----ADPD--------AIDLLEKMLVFDPRKRISAADALAHNYLAPYHDPTD 307

Human   368 VEAPPPQIYDKQLDEREHTIEEWKELIYKEVMN 400
             |....:::|....:.:..:|.||.::|.||::
pombe   308 -EPVADEVFDWSFQDNDLPVETWKVMMYSEVLS 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK10	NP_001304998.1	STKc_JNK	63..398	CDD:270840	148/338 (44%)
		S_TKc	64..359	CDD:214567	138/298 (46%)
sty1	NP_592843.1	STKc_Sty1_Hog1	9..336	CDD:270843	149/347 (43%)
		S_TKc	20..299	CDD:214567	138/298 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960