Protein Alignment MAPK9 and p38a

DIOPT Version :9

• Sequence 1: NP_001351537.1
• Gene: MAPK9 / 5601
• HGNCID: 6886
• Length: 424
• Species: Homo sapiens
• Sequence 2: NP_001163711.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 177/379 - (46%)
• Similarity: 243/379 - (64%)
• Gaps: 31/379 - (8%)

Human     9 QFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRE 73
            :||.:.:..:.:.:...||.|:|:||||.|.|..|......::||:|||:||||:..||||.|||
  Fly     8 KFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRE 72

Human    74 LVLLKCVNHKNIISLLNVFTPQK---TLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLLYQ 134
            |.|||.::|:|:|.||::|.|..   :||.||.||||..||||:|..:|.|: |..:.:.:|:||
  Fly    73 LRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQ 137

Human   135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILG 199
            :|.|:|::||||:||||||||||.|..||.|:||||||||.  |...||.||.||:|||||::|.
  Fly   138 ILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARP--TENEMTGYVATRWYRAPEIMLN 200

Human   200 -MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVEN 262
             |.|.:.||||||||||.||:....:|.|||||.|.|.::|.||||.|||:||: ..:.|:|:::
  Fly   201 WMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQS 265

Human   263 RPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP 327
            .|...|..|:.:|            |.....|.|||.|||.:|.:|||:.:|||.|||:..:.:|
  Fly   266 LPPMKGRSFKNVF------------KNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEP 318

Human   328 AEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSDAAV 381
            :..:..||  ||...|:.:..:::|||||||||.::         |..||.|.|
  Fly   319 SVEQTSPP--YDHSFEDMDLPVDKWKELIYKEVTNF---------KPPPSYAQV 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK9	NP_001351537.1	STKc_JNK	25..360	CDD:270840	168/340 (49%)
		TXY	183..185		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..424		5/14 (36%)
p38a	NP_001163711.1	STKc_p38	9..354	CDD:143356	172/369 (47%)
		S_TKc	25..312	CDD:214567	154/300 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910