Protein Alignment MAPK9 and rl

DIOPT Version :9

• Sequence 1: NP_001351537.1
• Gene: MAPK9 / 5601
• HGNCID: 6886
• Length: 424
• Species: Homo sapiens
• Sequence 2: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 387
• Identity: 147/387 - (37%)
• Similarity: 232/387 - (59%)
• Gaps: 46/387 - (11%)

Human    12 SVQVADSTFTVLK--------RYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAK 68
            |.:|..|...|::        ||.:|..||.||.|:|.:|.||:....||:||:| ||::||:.:
  Fly    16 STEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQTYCQ 79

Human    69 RAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLL 132
            |..||:.:|....|:|||.:.::.... ::::.:|||:|..||:.:|.:::..: |.::.:.|.|
  Fly    80 RTLREITILTRFKHENIIDIRDILRVD-SIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFL 143

Human   133 YQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA-----CTNFMMTPYVVTRYYR 192
            ||:|.|:|::|||.::||||||||:::...|.|||.||||||.|     .|.| :|.||.||:||
  Fly   144 YQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGF-LTEYVATRWYR 207

Human   193 APEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMK-KLQPT 255
            |||::| ..||.:::||||||||:.|::....||.|..::||.|.::..||:||.:.:: .:...
  Fly   208 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEK 272

Human   256 VRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPY 320
            .|||:|:.|..|.:.:.:|||:            ..:.|.|||.|||..:|.|||.|:|||.|||
  Fly   273 ARNYLESLPFKPNVPWAKLFPN------------ADALALDLLGKMLTFNPHKRIPVEEALAHPY 325

Human   321 ITVWYDPAE---AEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSDA 379
            :..:|||.:   ||.|    :...:|..:.:.:..|.||::|.:.::||        ||.:|
  Fly   326 LEQYYDPGDEPVAEVP----FRINMENDDISRDALKSLIFEETLKFKER--------QPDNA 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK9	NP_001351537.1	STKc_JNK	25..360	CDD:270840	137/345 (40%)
		TXY	183..185		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..424		3/12 (25%)
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	138/352 (39%)
		S_TKc	38..326	CDD:214567	125/302 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920