Protein Alignment MAPK9 and p38c

DIOPT Version :10

• Sequence 1: NP_002743.3
• Gene: MAPK9 / 5601
• HGNCID: 6886
• Length: 424
• Species: Homo sapiens
• Sequence 2: NP_996277.1
• Gene: p38c / 2768679
• FlyBaseID: FBgn0267339
• Length: 356
• Species: Drosophila melanogaster
• Alignment Length: 368
• Identity: 144/368 - (39%)
• Similarity: 211/368 - (57%)
• Gaps: 36/368 - (9%)

Human     9 QFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGIN--VAVKKLSRPFQNQTHAKRAY 71
            :|..|.:.:|.:.....|:.::.:|.|:.|.|...  .:.|..  .|:|:|.|||:.:..||..|
  Fly     3 EFVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKV--RLRGTENYFAMKRLMRPFEREEDAKGTY 65

Human    72 RELVLLKCVNHKNIISLLNVF-TPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMS-----Y 130
            ||:.|||.:||:|:||||||| .|...:.|||.||||..||||:|    |.....:|||     .
  Fly    66 REIRLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADL----HRYSRSKRMSDQEIRI 126

Human   131 LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPE 195
            :|||:|.|:|::||||::||||||.||.|..:..::||||||:| .|.: .||.:|.|.:|.|||
  Fly   127 ILYQILRGLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSR-MCAD-KMTDHVGTMWYLAPE 189

Human   196 VILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRN 258
            :|...| |.:.:|:||||||:.||:...|:|:|.:::.|...:|..:|||:.||:..: ....||
  Fly   190 IIFLRGQYTKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRN 254

Human   259 YVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITV 323
            |:|..|......|..||..:            ..||.||:.|||.:.|:|||:..||:.|||:..
  Fly   255 YLEGYPLRQRCDFHHLFMGY------------DVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRD 307

Human   324 WYDP---AEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDW 363
            ..:|   ||..||   :||...|.....::.||||:..|:.::
  Fly   308 LIEPHHHAEDTAP---VYDQNFENMVLPVKCWKELVSHEIRNF 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK9	NP_002743.3	STKc_JNK	25..360	CDD:270840	140/347 (40%)
		TXY	183..185		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..424
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	144/367 (39%)