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Protein Alignment MAPK11 and rl

DIOPT Version :9

Sequence 1:	NP_002742.3	Gene:	MAPK11 / 5600	HGNCID:	6873	Length:	364	Species:	Homo sapiens
Sequence 2:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	165/348 - (47%)
Similarity:	231/348 - (66%)	Gaps:	9/348 - (2%)

- Green bases have known domain annotations that are detailed below.

Human    17 VWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
            ::||..|...|..:|.||||.|.||.|....|:||:||:| ||:...:.:||.||:.:|...|||
  Fly    31 IFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITILTRFKHE 94

Human    82 NVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGI 146
            |:|.:.|:.. ..||:...:||:|..||..||..::|.|.||::|:.:.:||:||||||||||.:
  Fly    95 NIIDIRDILR-VDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANV 158

Human   147 IHRDLKPSNVAVNEDCELRILDFGLARQADEE------MTGYVATRWYRAPEIMLNWMHYNQTVD 205
            :||||||||:.:|:.|:|:|.||||||.||.|      :|.|||||||||||||||...|.:::|
  Fly   159 LHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSID 223

Human   206 IWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDL 270
            |||||||:||:|..:.:|||..|:|||..|:.|:|:||.:.|..|.:|.||.|::|||..|....
  Fly   224 IWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPW 288

Human   271 SSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAE-PYDESVEAKERTL 334
            :.:|..|:.||:||||:||..:..:|:...|||||.|..||:||.|||.|| |:..::|..:.:.
  Fly   289 AKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDDISR 353

Human   335 EEWKELTYQEVLSFKPPEPPKPP 357
            :..|.|.::|.|.||..:|...|
  Fly   354 DALKSLIFEETLKFKERQPDNAP 376

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.