Protein Alignment MAPK7 and p38a

DIOPT Version :9

• Sequence 1: XP_006721620.1
• Gene: MAPK7 / 5598
• HGNCID: 6880
• Length: 822
• Species: Homo sapiens
• Sequence 2: NP_001163711.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Alignment Length: 349
• Identity: 163/349 - (46%)
• Similarity: 230/349 - (65%)
• Gaps: 18/349 - (5%)

Human    49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
            :::.|.|:.::.:|:||||.||.|..|.|...|||||:...|....:||||.|||::|||..|:|
  Fly    19 WEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHEN 83

Human   114 IIAIKDILRPTVPYG---EFKSVPYGVPGYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRG 175
            :|.:.||..|....|   .|:.|      |:|..||::||:.||. .|.|:.:||::.:||:|||
  Fly    84 VIGLLDIFHPHPANGSLENFQQV------YLVTHLMDADLNNIIR-MQHLSDDHVQFLVYQILRG 141

Human   176 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML 240
            |||:|||.||||||||||:.|||:|||:|.|||:||     |.|::  ||.|||||||||||:||
  Fly   142 LKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR-----PTENE--MTGYVATRWYRAPEIML 199

Human   241 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQ 305
            :...|.|.:|:||||||..|::.||.||||.:::|||.|||.:||||....::.:.:|..|:|||
  Fly   200 NWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQ 264

Human   306 SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFD 370
            ||||.:...::.|:..|:..|:.||.:||..:...||:|..||.||:|.||.:|..| ..:||:|
  Fly   265 SLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVE-QTSPPYD 328

Human   371 FAFDREALTRERIKEAIVAEIEDF 394
            .:|:...|..::.||.|..|:.:|
  Fly   329 HSFEDMDLPVDKWKELIYKEVTNF 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK7	XP_006721620.1	STKc_ERK5	49..390	CDD:270842	161/343 (47%)
		S_TKc	55..353	CDD:214567	147/300 (49%)
p38a	NP_001163711.1	STKc_p38	9..354	CDD:143356	163/349 (47%)
		S_TKc	25..312	CDD:214567	147/300 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810