Protein Alignment SLC25A40 and CG4743

DIOPT Version :10

• Sequence 1: NP_061331.2
• Gene: SLC25A40 / 55972
• HGNCID: 29680
• Length: 338
• Species: Homo sapiens
• Sequence 2: NP_651415.1
• Gene: CG4743 / 43101
• FlyBaseID: FBgn0039357
• Length: 297
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 70/324 - (21%)
• Similarity: 135/324 - (41%)
• Gaps: 68/324 - (20%)

Human     8 QEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEG 72
            :.:.|:.....::|.....::..:.:.|:|.||.|||::
  Fly    20 EPVNKLKFFHALVAGGVAGMVVDIALFPIDTVKTRLQSE-------------------------- 58

Human    73 GNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYD----QLSALLR 133
               |.:.:.|.|:|                ::.||.|....:.|...::|..|:    .||::.:
  Fly    59 ---LGFWRAGGFRG----------------IYKGLAPAAAGSAPTAALFFCTYECGKQFLSSVTQ 104

Human   134 SKLGENETCIPIVAGIVARFGAVTVISPLELIRTK---MQSKKFSYVE--LHRFVSKKVSEDGWI 193
            :|   :...:.:.|...|...|..:..|:|:.:.:   :|..|.|.::  |..:.::.:..
  Fly   105 TK---DSPYVHMAAASAAEVLACLIRVPVEIAKQRSQTLQGNKQSGLQILLRAYRTEGLKR---- 162

Human   194 SLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDV 258
            .|:||:..|::|::|||.:.:..:|..|......:|.....|.:.. .||::|..:|..|.|.||
  Fly   163 GLYRGFGSTIMREIPFSLIQFPLWEYFKLQWTPLTGFDSTPFSVAL-CGAVAGGISAGLTTPLDV 226

Human   259 VKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYE 322
            |||:...      :.:.|:....|...|:..|..:.||||||:|.:||::.|....|.....|:
  Fly   227 VKTRIML------AERESLNRRRSARRILHGIYLERGFSGLFAGFVPRVLWITLGGAFFFGFYD 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A40	NP_061331.2	Mito_carr	12..136	CDD:395101	21/127 (17%)
		Solcar 1	13..131		20/121 (17%)
		Solcar 2	139..223		19/88 (22%)
		Mito_carr	145..228	CDD:395101	19/87 (22%)
		Mito_carr	231..330	CDD:395101	28/92 (30%)
		Solcar 3	233..327		28/90 (31%)
CG4743	NP_651415.1	PTZ00168	25..281	CDD:185494	68/314 (22%)