DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC25A40 and Rim2

DIOPT Version :10

Sequence 1:NP_061331.2 Gene:SLC25A40 / 55972 HGNCID:29680 Length:338 Species:Homo sapiens
Sequence 2:NP_608615.1 Gene:Rim2 / 33350 FlyBaseID:FBgn0031359 Length:365 Species:Drosophila melanogaster


Alignment Length:364 Identity:86/364 - (23%)
Similarity:158/364 - (43%) Gaps:59/364 - (16%)


- Green bases have known domain annotations that are detailed below.


Human    16 LQQMLASCTGAILTSVIVTPLDVVKIRLQAQN-----NPLPKGKCFVYSNGLMDHLCVCEE---- 71
            |..::|..:...:.:|:..||:|||.|||:..     :.|.:......:||....|...|:    
  Fly     9 LIHLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANGGQSELLRPEQRRKL 73

Human    72 ---------------GGNKLWYKKPGNFQGT-------LDAFFKIIRNEGIKSLWSGLPPTLVMA 114
                           |..::..........|       :.....|::|||.::|:.||.|.||..
  Fly    74 STTILRNRSQPQVIGGVRRIMAISHCGISSTTPKSMSIVQCLRHIVQNEGPRALFKGLGPNLVGV 138

Human   115 VPATVIYFTCYDQLSALLRSKLGENETCIPIV---AGIVARFGAVTVISPLELIRTKMQSKKFSY 176
            .|:..|||..|.|....|.| ||..|...|:|   :...|.|.:.|..:|:..::|:||....|.
  Fly   139 APSRAIYFCTYSQTKNTLNS-LGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQLDYNSK 202

Human   177 VEL--HRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILK-KWLCEKSGLYEPT---- 234
            |::  .:.:.:..::.|..:.::|...:.. .:..:.:::..||.:| |.|.:::..:..|    
  Fly   203 VQMTVRQCIERVYAQGGVAAFYKGITASYF-GICETMVHFVIYEFIKSKLLEQRNQRHTDTKGSR 266

Human   235 -FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSG 298
             |:....:||:|.:.|:....|.:|.:|:.:.     |.:|     :.|.|..:..:..:.|.:|
  Fly   267 DFLEFMMAGAVSKTIASCIAYPHEVARTRLRE-----EGNK-----YNSFWQTLHTVWKEEGRAG 321

Human   299 LFSGLIPRLIKIAPACAIMISTYE-----FGKAFFQKQN 332
            |:.||..:|::..|..|||::|||     ..:.|..|.|
  Fly   322 LYRGLATQLVRQIPNTAIMMATYEAVVYVLTRRFNNKSN 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC25A40NP_061331.2 Mito_carr 12..136 CDD:395101 36/150 (24%)
Solcar 1 13..131 34/145 (23%)
Solcar 2 139..223 17/89 (19%)
Mito_carr 145..228 CDD:395101 17/88 (19%)
Mito_carr 231..330 CDD:395101 27/108 (25%)
Solcar 3 233..327 26/103 (25%)
Rim2NP_608615.1 Mito_carr 8..156 CDD:395101 34/146 (23%)
Mito_carr 163..253 CDD:395101 18/90 (20%)
Mito_carr 268..355 CDD:395101 25/96 (26%)

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