DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC25A40 and mtm1

DIOPT Version :10

Sequence 1:NP_061331.2 Gene:SLC25A40 / 55972 HGNCID:29680 Length:338 Species:Homo sapiens
Sequence 2:NP_595818.1 Gene:mtm1 / 2541312 PomBaseID:SPBP23A10.06 Length:335 Species:Schizosaccharomyces pombe


Alignment Length:350 Identity:116/350 - (33%)
Similarity:178/350 - (50%) Gaps:73/350 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    13 VTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQN-------NPLPKGKCFVYSNGLMDHLCVCE 70
            |.|:.:||::|.|:::|::.||||||||.|||:::       .|:...|  :...|         
pombe    22 VKPIAKMLSACVGSVITTLTVTPLDVVKTRLQSESISQYSSTQPISSAK--ILGKG--------- 75

Human    71 EGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSK 135
                   ...|....|.:...::|.|:||::|||.||.|:|.|.:||..:.|..|:||..|.   
pombe    76 -------RPAPKPLGGPVSGLYQIARHEGVRSLWRGLVPSLTMLLPANTVQFLGYEQLLPLY--- 130

Human   136 LGENETCIP---IVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELH-RFVSKKV--------S 188
               ::...|   .:||..||..:.|::||:||.||::|:....|...| |.::.:|        .
pombe   131 ---SDWGFPAAAAIAGASARTISATIVSPIELFRTRVQAVGGHYPPGHAREIANEVFDGLKLMIH 192

Human   189 EDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFM------------INFTS 241
            :.|.::||.|.:.|:.|||||||.||::||.::.:|     |..|:..            |||.|
pombe   193 QKGILNLWSGVSVTLWRDVPFSAFYWWSYERIRLFL-----LGHPSLQAFSSSQSTKDLYINFVS 252

Human   242 GALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMST-WIIMKNIVAKNGFSGLFSGLIP 305
            |.:||:.|.:.|.||||.||.||.     ..|.::....|.| |       .:.|...|:.|.:|
pombe   253 GGISGTLATLLTQPFDVSKTAKQV-----HGHTLTRGQFMLTLW-------KRGGPKALWKGTLP 305

Human   306 RLIKIAPACAIMISTYEFGKAFFQK 330
            |.:|:||:||||||:|...|.:|.:
pombe   306 RCVKVAPSCAIMISSYHLTKKYFSE 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC25A40NP_061331.2 Mito_carr 12..136 CDD:395101 42/129 (33%)
Solcar 1 13..131 41/124 (33%)
Solcar 2 139..223 33/95 (35%)
Mito_carr 145..228 CDD:395101 33/91 (36%)
Mito_carr 231..330 CDD:395101 39/111 (35%)
Solcar 3 233..327 38/106 (36%)
mtm1NP_595818.1 Mito_carr 21..132 CDD:395101 42/133 (32%)
Mito_carr 148..231 CDD:395101 30/87 (34%)
Mito_carr 242..331 CDD:395101 38/100 (38%)

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