Protein Alignment LIN37 and mip40

DIOPT Version :10

• Sequence 1: NP_061977.1
• Gene: LIN37 / 55957
• HGNCID: 33234
• Length: 246
• Species: Homo sapiens
• Sequence 2: NP_611407.1
• Gene: mip40 / 37215
• FlyBaseID: FBgn0034430
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 230
• Identity: 62/230 - (26%)
• Similarity: 103/230 - (44%)
• Gaps: 36/230 - (15%)

Human    29 LLEKSHMDRE---RLDEE-----AGKTPSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLA 85
            ||.:....|:   :||.:     :|.:...:.:...:.|..|.|..||   :...|:......:|
  Fly    49 LLIQQQQQRQYQVKLDPKVKTVTSGSSEKPSTSSSAAAAGAGGRIKAR---RVLYKKSVGAAAVA 110

Human    86 EGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERECSPS-------SPLPPL 143
            :..|  ..|||::||:||:||:::.:.|||||||||||.|.|.      :|:       :.|...
  Fly   111 QKAP--GETYVMRLFERSLDLSKYQDKTPLYPICRAWMANQPK------NPAVGAFQTDASLTAT 167

Human   144 PEDEEGSEVTNSKSRDVYKLPPPTPPGPPGDACRSRIPSPLQPEMQGTPDDEPSEPE---PSPST 205
            ..::.|.|:.:.......|:....|.....|     :|. :.|.::.:.:|:..|..   .|.|.
  Fly   168 KREDNGEEILSQIKSGEIKVINQLPQAKSTD-----LPI-IPPRLEFSQEDKKREKALQGASTSD 226

Human   206 LIYRNMQRWKRIRQRW-KEASHRNQLRYSESMKIL 239
            |:..||.|||::|..| |......:.||....||:
  Fly   227 LLSSNMNRWKKVRGHWIKHIKKYEKERYEVIDKIM 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIN37	NP_061977.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..90		11/60 (18%)
		LIN37	84..240	CDD:464632	50/167 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..209		14/89 (16%)
mip40	NP_611407.1	LIN37	108..262	CDD:464632	50/168 (30%)