DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZMAT5 and CG31922

DIOPT Version :9

Sequence 1:	NP_001003692.1	Gene:	ZMAT5 / 55954	HGNCID:	28046	Length:	170	Species:	Homo sapiens
Sequence 2:	NP_722687.1	Gene:	CG31922 / 319028	FlyBaseID:	FBgn0051922	Length:	139	Species:	Drosophila melanogaster

Alignment Length:	181	Identity:	47/181 - (25%)
Similarity:	74/181 - (40%)	Gaps:	56/181 - (30%)

- Green bases have known domain annotations that are detailed below.

Human     2 GKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQC 66
            ||.|:||||....:::|:.||.|..|:.|..||..:...:.|...||.:|:.|.||::: ....|
  Fly     3 GKSYYCDYCCCFLKNDLNVRKLHNGGIAHAIAKSNYLKRYEDPKKILTEERQKTPCKRY-FGSYC 66

Human    67 DFGSNCRFSHMSERDLQELSIQVEEERRAREWLLDAPELPEGHLEDWLEKRAKRLSSAPSSRAEP 131
            .|.:.|:|:|.|..:|:|                         ||..:..|.||.|...:::.:
  Fly    67 KFETYCKFTHYSGDNLRE-------------------------LEKLVLARKKRKSRKKTNKCK- 105

Human   132 IRTTVFQYPVGWP----PVQELPPSLRAPPPGGWPLQP--------RVQWG 170
                      .||    ..:.|||||:       |:.|        .:.||
  Fly   106 ----------RWPWKTHLRKGLPPSLQ-------PINPEKLKQTDFELSWG 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZMAT5	NP_001003692.1	zf-U1	4..>46	CDD:389966	14/41 (34%)
		zf-CCCH	55..76	CDD:395517	6/20 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	150..170		6/27 (22%)
CG31922	NP_722687.1	zf-U1	3..39	CDD:277622	15/35 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5136
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I5341
Isobase	1	0.950	-	0	Normalized mean entropy	S7282
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1541869at2759
OrthoFinder	1	1.000	-	-		FOG0007275
OrthoInspector	1	1.000	-	-		oto89587
orthoMCL	1	0.900	-	-		OOG6_106589
Panther	1	1.100	-	-	LDO	PTHR16465
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5190
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.740