Protein Alignment MAPK3 and p38b

DIOPT Version :9

• Sequence 1: NP_002737.2
• Gene: MAPK3 / 5595
• HGNCID: 6877
• Length: 379
• Species: Homo sapiens
• Sequence 2: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 162/346 - (46%)
• Similarity: 239/346 - (69%)
• Gaps: 18/346 - (5%)

Human    36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHEN 99
            :::...|..||.:|:||||.|..|......|:|||||:: ||:...:.:||.||:::|....|||
  Fly    18 WEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHEN 82

Human   100 VIGIRDILR----ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSA 160
            |||:.|:..    |.:|:..:.||:|..||:.||..::::|:||:||:.:.:|||||||||||||
  Fly    83 VIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSA 147

Human   161 NVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKS 225
            .|:||||||||:.:|..|:|:|.||||||.|:.|      :|.|||||||||||||||...|.::
  Fly   148 GVIHRDLKPSNIAVNEDCELRILDFGLARPAESE------MTGYVATRWYRAPEIMLNWMHYNQT 206

Human   226 IDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKV 290
            .||||||||:||:|:.|.:|||..::.|||.|:.:||:|:.|.::.|.:..||||::|||...:.
  Fly   207 ADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRR 271

Human   291 AWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVA---EEPFTFAMEL 352
            .:..:|..::..|:|||::||..:.:||||.|:||||||:|:|:|||||..|   ::.|    |.
  Fly   272 NFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSF----EE 332

Human   353 DDLPKERLKELIFQETARFQP 373
            ::||.|:.:|::|.|...|:|
  Fly   333 NELPVEKWREMVFSEVTAFKP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK3	NP_002737.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		STKc_ERK1_2_like	36..370	CDD:270839	160/341 (47%)
		TXY	202..204		1/1 (100%)
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	161/344 (47%)
		S_TKc	24..311	CDD:214567	143/292 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810