Protein Alignment PRKG2 and BCY1

DIOPT Version :9

• Sequence 1: XP_016863902.1
• Gene: PRKG2 / 5593
• HGNCID: 9416
• Length: 774
• Species: Homo sapiens
• Sequence 2: NP_012231.1
• Gene: BCY1 / 854778
• SGDID: S000001295
• Length: 416
• Species: Saccharomyces cerevisiae
• Alignment Length: 424
• Identity: 106/424 - (25%)
• Similarity: 197/424 - (46%)
• Gaps: 63/424 - (14%)

Human    23 TDALRNKVTELERELRRKDAEIQEREYHLK--------ELREQLSKQTVAIAE------------ 67
            :|.|:.......:.|.::.|.::.||...|        |..|..|:...|.::
Yeast    26 SDFLQFSANYFNKRLEQQRAFLKAREPEFKAKNIVLFPEPEESFSRPQSAQSQSRSRSSVMFKSP 90

Human    68 -LTEELQNKCIQ----LNKLQDVVHMQGGSPLQASPDKV---PLEVHRKTSGLVSLHSRRGAKAG 124
             :.|:..:...:    |:..:...|.|.....|.:.:|.   ||.:|...       .||.:.:|
Yeast    91 FVNEDPHSNVFKSGFNLDPHEQDTHQQAQEEQQHTREKTSTPPLPMHFNA-------QRRTSVSG 148

Human   125 VSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKL--ITDALNKNQFLKRLDPQQIKDMVECMYGR 187
            .:.:|  ..:|...|..:        |:.||::|  :..::..|....:||....:.::.|:..:
Yeast   149 ETLQP--NNFDDWTPDHY--------KEKSEQQLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEK 203

Human   188 NYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNV 252
            :..:|:.|||||:.|::.:|:.:|.::.:..:..::|....::|||||::||..|.|:|.|.::.
Yeast   204 SVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSSGPGSSFGELALMYNSPRAATVVATSDC 268

Human   253 KTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREG 317
            ..|||||..|:.|:..::..:...|.:.|:|:.:||:|......|:.|.|:.:.|..|:.|||||
Yeast   269 LLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREG 333

Human   318 EEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVI 382
            ::|..|:::..|.|.|::..:|     :|..|:..:||||.||::|..|.|.:.|
Yeast   334 DQGENFYLIEYGAVDVSKKGQG-----VINKLKDHDYFGEVALLNDLPRQATVTA---------- 383

Human   383 DRETFNQTVGTFEELQKYLEGYVANLNRDDEKRH 416
            .:.|...|:|. ...|:.|...|..|..:|..||
Yeast   384 TKRTKVATLGK-SGFQRLLGPAVDVLKLNDPTRH 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKG2	XP_016863902.1	None
BCY1	NP_012231.1	DD_R_PKA_fungi	7..44	CDD:213045	3/17 (18%)
		CAP_ED	184..282	CDD:237999	30/97 (31%)
		CAP_ED	302..409	CDD:237999	37/122 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810