Protein Alignment PRKG1 and inaC

DIOPT Version :10

• Sequence 1: NP_006249.1
• Gene: PRKG1 / 5592
• HGNCID: 9414
• Length: 686
• Species: Homo sapiens
• Sequence 2: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 108/314 - (34%)
• Similarity: 173/314 - (55%)
• Gaps: 10/314 - (3%)

Human   370 LKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQ-GAHS 433
            ::.:|||.:..:|.|.||:|.|.:.:..: :.:|:|:|:|..|:.|...|...:||:|:. ....
  Fly   366 IRAADFNFVKVIGKGSFGKVLLAERRGTD-ELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429

Human   434 DFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYR 498
            .|:|.::..|:....|:.:||.|.||:|...::..|.|::|...||...|..|..:||.:.||||
  Fly   430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYR 494

Human   499 DLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGIL 562
            |||.:|::||..|:.||||||.:|: :...:.|.||||||.|:||||:....:.|:||:||.|:|
  Fly   495 DLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVL 559

Human   563 MYELLTGSPPFSGPDPMKTYNIILRGI--DMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGV 625
            ::|.:.|..||.|.|.    ..:.|.|  ....|||..:..|.::|.......|:.|||..:...
  Fly   560 LFEFMAGQAPFEGDDE----TTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYAR 620

Human   626 KDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNF-DSFPEDNDEPPPDD 678
            ::|..|.:|...:|:......:.|||.|.:....|.||| |:|.::..:..|.|
  Fly   621 QEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTD 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKG1	NP_006249.1	DD_cGKI-beta	4..55	CDD:213375
		CAP_ED	118..227	CDD:237999
		CAP_ED	237..341	CDD:237999
		STKc_cGK	381..641	CDD:270724	93/263 (35%)
		S_TK_X	636..>679	CDD:214529	13/44 (30%)
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342
		C1	137..190	CDD:412127
		C2_PKC_alpha_gamma	194..324	CDD:175992
		STKc_PKC	375..692	CDD:270722	105/305 (34%)