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Protein Alignment PRKG1 and Pka-C1

DIOPT Version :9

Sequence 1:	NP_006249.1	Gene:	PRKG1 / 5592	HGNCID:	9414	Length:	686	Species:	Homo sapiens
Sequence 2:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	147/341 - (43%)
Similarity:	207/341 - (60%)	Gaps:	15/341 - (4%)

- Green bases have known domain annotations that are detailed below.

Human   340 IGGLDDVSNKAYEDAEA------KAKYEAEAAFFAN----LKLSDFNIIDTLGVGGFGRVELVQL 394
            :|.....|||..:.||.      :||.|.|..:..|    ..|.||..|.|||.|.||||.:||.
  Fly     1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQH 65

Human   395 KSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGG 459
            |..:. .:|||||.|:.:|..:|.||..:||:|:|.....|:|.|...|||:..|||::|...||
  Fly    66 KPTKD-YYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGG 129

Human   460 ELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI 524
            |:::.||..|.|.:..:|||.|.:|.||.|||...:||||||||||::|.:||.|:.||||||::
  Fly   130 EMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV 194

Human   525 GFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGI 589
              ..:|||.||||||:||||||:||::.:.|:|:||:|:||:..|.|||....|::.|..|:.|
  Fly   195 --KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSG- 256

Human   590 DMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPS 654
             .:.||.....:..:|::.|.:.:.::|.||||.||.||:..|||...:|..:.:..:..|.||.
  Fly   257 -KVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPR 320

Human   655 VASPTDTSNFDSFPED 670
            ...|.||||||.:.|:
  Fly   321 CKGPGDTSNFDDYEEE 336

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.