Protein Alignment PRKG1 and Prkg1

DIOPT Version :10

• Sequence 1: NP_006249.1
• Gene: PRKG1 / 5592
• HGNCID: 9414
• Length: 686
• Species: Homo sapiens
• Sequence 2: NP_035290.1
• Gene: Prkg1 / 19091
• MGIID: 108174
• Length: 686
• Species: Mus musculus
• Alignment Length: 686
• Identity: 683/686 - (99%)
• Similarity: 685/686 - (99%)
• Gaps: 0/686 - (0%)

Human     1 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQAQKQSA 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQAQKQSA 65

Human    66 STLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEI 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 STLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEI 130

Human   131 VDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTAT 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 VDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTAT 195

Human   196 VKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENG 260
            ||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||
Mouse   196 VKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPDEILSKLADVLEETHYENG 260

Human   261 EYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEA 325
            |||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 EYIIRQGARGDTFFIISKGQVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEA 325

Human   326 VTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVE 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 VTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVE 390

Human   391 LVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEA 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   391 LVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEA 455

Human   456 CLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGF 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   456 CLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGF 520

Human   521 AKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNII 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 AKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNII 585

Human   586 LRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 650
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   586 LRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 650

Human   651 IIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF 686
            ||||||||||||||||||||:|||||||||||||||
Mouse   651 IIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKG1	NP_006249.1	DD_cGKI-beta	4..55	CDD:213375	50/50 (100%)
		CAP_ED	118..227	CDD:237999	108/108 (100%)
		CAP_ED	237..341	CDD:237999	101/103 (98%)
		STKc_cGK	381..641	CDD:270724	259/259 (100%)
		S_TK_X	636..>679	CDD:214529	41/42 (98%)
Prkg1	NP_035290.1	DD_cGKI-beta	4..55	CDD:213375	50/50 (100%)
		CAP_ED	118..227	CDD:237999	108/108 (100%)
		CAP_ED	237..341	CDD:237999	101/103 (98%)
		STKc_cGK	381..641	CDD:270724	259/259 (100%)
		S_TK_X	636..>679	CDD:214529	41/42 (98%)