Protein Alignment exoc5 and Sec10

DIOPT Version :9

• Sequence 1: NP_001107268.1
• Gene: exoc5 / 559010
• ZFINID: ZDB-GENE-080204-126
• Length: 708
• Species: Danio rerio
• Sequence 2: NP_651218.1
• Gene: Sec10 / 42863
• FlyBaseID: FBgn0266673
• Length: 710
• Species: Drosophila melanogaster
• Alignment Length: 694
• Identity: 288/694 - (41%)
• Similarity: 445/694 - (64%)
• Gaps: 10/694 - (1%)

Zfish     9 EEPFDADEYIERLAWRTPGGGSKGGAEAFDPKKLLEEFVNHIEELKLLDERIQRKVEKLEQQCHR 73
            :|||:..|:||||.|||  ......:|.|.|..|.:.|:..|::||:|.|:.|.|.|:||:...:
  Fly    11 QEPFEVGEFIERLTWRT--NNELQNSEDFHPVALHDTFIQTIKDLKILQEKQQSKCERLEESLRQ 73

Zfish    74 EAKEFAHKVQDLQRSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQRLMTYFN 138
            |.:..|.|:..||..:|.|...|.:|||.|:.||.|:.|||:|||.|||||.|:||||:|:.:.:
  Fly    74 EKESHAKKIAKLQERHQTAIDVFGQLDEKINSVAGKIMHLGEQLENVNTPRSRSVEAQKLLNFMS 138

Zfish   139 EFLDG--ELRSDVFNNPEKIKEAADIIQKLHLIAQELPFDRFSDVKAKIASKYHDLERQLIQEFT 201
            |||..  .:.:|:|.:..::.||||:||||:.|:|:||...|::.|.||..||.::||:||:||.
  Fly   139 EFLAAGPVIVNDIFADAARLSEAADVIQKLYAISQDLPPGNFAESKRKIEKKYDEVERRLIEEFA 203

Zfish   202 AAQRRGEIGRMREVAAVLLHFKGYAHCVDVYIKQCQEGAYMRNDVFEDIAILCQRVNKQVGEVFC 266
            .||:..:|.||:.:|.:|..||||..|||.||:|.|...|...|:|..|..||:...:.:.:||.
  Fly   204 TAQKSEDIERMKTLAQILSQFKGYTQCVDAYIEQSQMQPYSGKDIFIGIVPLCKHHYEIIQKVFA 268

Zfish   267 SPETVMAKLIQSIFENKIQAHVKERLDETRNSDVEQYLKNLYDLYTRTTALAAKLTDYNLGSDKH 331
            :|:.||:|.|.:|::.|:..:...:|::.:  |.|:||:.||:||:||..|:..|..| :.:...
  Fly   269 NPQQVMSKFILNIYQLKLHQYAMTKLEDKK--DEEKYLRTLYELYSRTLKLSTDLQIY-MSTIDD 330

Zfish   332 TFLSKLIKNIFSCYLESYIDMERQYLQNRSGMILQRYYDSKNHQKRPVGTGSIQELKERIRQRTN 396
            ..|.||.:.||..:|..|.:||.:.|..:....|:::|.||.|||.....|..:.::..|..|.|
  Fly   331 DLLQKLTQQIFIKHLAGYAEMETKCLTAKCSTELEKFYASKKHQKTATTKGFRRNMEVLIATRAN 395

Zfish   397 LPLGPSIDTHGETLLSQEVVVNLLQETRHAFERCNKLSDPADLPKNAFSIFLILVEYLCVDHIDY 461
            :.:....|..|||.||:|:.:|:|||.:.:.:||..||:..:||.||..:..||:.:|..:|:||
  Fly   396 INIAAIEDYGGETFLSEELAINMLQEAKASLKRCRLLSNETELPGNAIKLNDILLRFLMHEHVDY 460

Zfish   462 ALEIGLSAIPSADAK-NANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLTECLHKKKEVI 525
            |||:||.|:|.|:.: ...|||.||||:.|.|.||.||..:..::|.:|::||.::.:.||:.::
  Fly   461 ALELGLQAVPLAEGRVFPQLYFFDVVQKTNIIVHLLDKLCHTSVIPCVSNTPKYSDYVFKKRILM 525

Zfish   526 EQMEVKLDTGIDRTLNCMIGQMKYILTTEQKKTDFKPEDENNVMIQYTTACSKVCAYVGKQVERV 590
            ||:|.|||.|:||:::.:||.:|..|..||||||:|||.:.:.:  .:.||.:|...:...:.::
  Fly   526 EQIETKLDQGLDRSISAVIGWVKVYLQYEQKKTDYKPETDVDTI--SSAACLQVVQNLQPVIVQI 588

Zfish   591 RRSMDGKNVDTVLTELGVRFHRLIHEHLQQFSYSSMGGMLAICDVAEYRRSAKDFRVPLVLQLFD 655
            ::.:||:|:..||||.|.|.||:|::|||...:::.|.|.|||||.|||:..::...|||.||||
  Fly   589 KKCVDGENLQNVLTEFGTRLHRVIYDHLQTMQFNTAGAMCAICDVNEYRKCIRELDSPLVTQLFD 653

Zfish   656 TLHALCNLLVVAPDNLKQVCSGEQLTNLDRNLLHAFVQLRVDYR 699
            .||||||||:|.|.||::||:|:.|..||::::..|:|||.|:|
  Fly   654 ILHALCNLLLVKPQNLQEVCTGDTLNYLDKSVVRQFIQLRTDFR 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exoc5	NP_001107268.1	Sec10	89..707	CDD:284746	257/614 (42%)
Sec10	NP_651218.1	RILP-like	46..>103	CDD:304877	22/56 (39%)
		Sec10	89..705	CDD:284746	257/614 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587111
Domainoid	1	1.000	498	1.000	Domainoid score	I344
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38195
Inparanoid	1	1.050	555	1.000	Inparanoid score	I1086
OMA	1	1.010	-	-		QHG54308
OrthoDB	1	1.010	-	-		D225235at2759
OrthoFinder	1	1.000	-	-		FOG0004379
OrthoInspector	1	1.000	-	-		oto39504
orthoMCL	1	0.900	-	-		OOG6_102983
Panther	1	1.100	-	-	LDO	PTHR12100
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2282
SonicParanoid	1	1.000	-	-		X5499
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940