DRSC/TRiP Functional Genomics Resources

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Protein Alignment PBK and PKH1

DIOPT Version :9

Sequence 1:NP_001265874.1 Gene:PBK / 55872 HGNCID:18282 Length:333 Species:Homo sapiens
Sequence 2:NP_010778.3 Gene:PKH1 / 852101 SGDID:S000002898 Length:766 Species:Saccharomyces cerevisiae


Alignment Length:336 Identity:77/336 - (22%)
Similarity:125/336 - (37%) Gaps:98/336 - (29%)


- Green bases have known domain annotations that are detailed below.


Human    34 FMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHY--RSVYQKRLMDEAKILKSLHHPN 96
            |.::||.|:..:|.|......|   ..:|||    :.:..|  |....|.:..|...|:.|:...
Yeast   127 FGEQLGDGSYSSVVLATARDSG---KKYAVK----VLSKEYLIRQKKVKYVTVEKLALQKLNGTK 184

Human    97 IVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEE---------RYKASQDPFPAAIILKVALNMAR 152
            .:....||..::.||...:||........||::         ||.|||              :..
Yeast   185 GIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQ--------------IID 235

Human   153 GLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVS--LPLDENMTA---PAFITILLVSVTD 212
            .:..|| ...::|.|||..|:::..:.: :|:.|.|.:  ||.:.:.||   |.|      .:..
Yeast   236 AVDSLH-NIGIIHRDIKPENILLDKNMK-VKLTDFGTAKILPEEPSNTADGKPYF------DLYA 292

Human   213 PEACYIGTEPWKPKEAVEENGVITD-KADIFAFGLTLWEMM------------------------ 252
            ....::||..:...|.:.:|  .|| :.||:|||..|::|:                        
Yeast   293 KSKSFVGTAEYVSPELLNDN--YTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYA 355

Human   253 -TLSIPHI-------NLSNDDDDE--------DKTFDESDFDDEAYYAALGTRPP------INME 295
             |...|.|       .|..|.:|.        ...|.|.:|:|.:.:   ...||      ||.|
Yeast   356 FTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFEDGSVW---DDNPPEIQPYKINAE 417

Human   296 ELDESYQKVIE 306
            .: :..|||.|
Yeast   418 AM-KPLQKVSE 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PBKNP_001265874.1 PKc_TOPK 32..332 CDD:270903 77/336 (23%)
Pkinase 34..327 CDD:278497 77/336 (23%)
PKH1NP_010778.3 STKc_PDK1 123..391 CDD:270733 64/294 (22%)
S_TKc 125..391 CDD:214567 64/294 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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