Protein Alignment PBK and zak-1

DIOPT Version :9

• Sequence 1: NP_001265874.1
• Gene: PBK / 55872
• HGNCID: 18282
• Length: 333
• Species: Homo sapiens
• Sequence 2: NP_001367790.1
• Gene: zak-1 / 175954
• WormBaseID: WBGene00006971
• Length: 745
• Species: Caenorhabditis elegans
• Alignment Length: 330
• Identity: 81/330 - (24%)
• Similarity: 137/330 - (41%)
• Gaps: 74/330 - (22%)

Human    23 STPTINIPAS------------PFMQK--------LGFGTGVNVYLMKRS-PRGLSHSPWAVKKI 66
            ||||.|...|            |.:|:        :|.||...|:....: |.| |....|:||:
 Worm     2 STPTSNESTSSSSNNSDQRVLFPDIQRDDIQVGDHIGVGTFGAVFSGNWTLPDG-SQRTIALKKV 65

Human    67 NPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLI---- 127
                     .|.:|    ||:||..:.|.||:.:....:|......:..||..:.||.|.|
 Worm    66 ---------FVLEK----EAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEE 117

Human   128 EERYKASQDPFPAAIILKVALNMARGLKYLHQE--KKLLHGDIKSSNVVIKGDFETIKICDVGVS 190
            .:.:.:|.......:::|.|..:|.|::|||.:  ..::|.|:||.|||:..:. ..||||.|.|
 Worm   118 SQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNL-VCKICDFGTS 181

Human   191 LPLDENMTAPAFITILLVSVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLS 255
            ..|..:.|||:               :.||..|...|.:.::..:|...|::::|:.|||:::..
 Worm   182 KDLTHSCTAPS---------------WGGTAAWMSPEMILQSEGLTTATDVWSYGVVLWEILSKE 231

Human   256 IPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRP 320
            :|:                .|:.:...:..: |:..|.:.........:.:|.|.|....||||.
 Worm   232 VPY----------------KDYSEFRIFTMI-TQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRA 279

Human   321 SAAHI 325
            :...|
 Worm   280 NMRQI 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PBK	NP_001265874.1	PKc_TOPK	32..332	CDD:270903	76/321 (24%)
		Pkinase	34..327	CDD:278497	74/307 (24%)
zak-1	NP_001367790.1	PKc_like	38..291	CDD:419665	73/294 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910