DRSC/TRiP Functional Genomics Resources

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Protein Alignment PBK and sel-15

DIOPT Version :9

Sequence 1:NP_001265874.1 Gene:PBK / 55872 HGNCID:18282 Length:333 Species:Homo sapiens
Sequence 2:NP_001366799.1 Gene:sel-15 / 175225 WormBaseID:WBGene00016030 Length:847 Species:Caenorhabditis elegans


Alignment Length:312 Identity:78/312 - (25%)
Similarity:127/312 - (40%) Gaps:60/312 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    34 FMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSV------YQKRLMDEAKILKSL 92
            |.:.:|.|:...||  |.:.||   ...|||:        ||::      ....|..|..||..|
 Worm   518 FQESIGSGSFGKVY--KGTYRG---KLVAVKR--------YRAMAFGCKSETDMLCREVSILSRL 569

Human    93 HHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYL 157
            .|||:|.:...:..:.....:..|:....||..|:.|. |...||   |..|:::|::|||::||
 Worm   570 AHPNVVAFVGTSLDDPSQFAIITEFVENGSLFRLLHEE-KRVMDP---AFRLRISLDVARGMRYL 630

Human   158 HQE--KKLLHGDIKSSNVVIKGDFETIKICDVGVSLPL----DENMTAPAFITILLVSVTDPEAC 216
            |:.  |.::|.|:.|.|::|..|..:: :.|.|.|..:    |||:|...               
 Worm   631 HESAAKPVIHRDLNSHNILIHADGRSV-VADFGESRFVCQREDENLTKQP--------------- 679

Human   217 YIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEA 281
              |...|...|...::|....|.|:|:|.|.:||:.|..:|..:|.......:.|:...      
 Worm   680 --GNLRWMAPEVFSQSGKYDRKVDVFSFALVIWEIHTAELPFSHLKPAAAAAEMTYKRG------ 736

Human   282 YYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALETDV 333
                   ||.:..:...:....::.|.....:.:...||....||..||..|
 Worm   737 -------RPTLPNQPTAQFPAHILSLIPQAWHPESSSRPDFVEIVALLEPHV 781

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PBKNP_001265874.1 PKc_TOPK 32..332 CDD:270903 77/309 (25%)
Pkinase 34..327 CDD:278497 74/304 (24%)
sel-15NP_001366799.1 ANKYR 3..217 CDD:223738
ANK repeat 115..147 CDD:293786
PHA03095 128..>388 CDD:222980
ANK repeat 153..180 CDD:293786
ANK repeat 182..213 CDD:293786
ANK repeat 215..246 CDD:293786
ANK repeat 285..318 CDD:293786
ANK repeat 320..353 CDD:293786
ANKYR <323..458 CDD:223738
ANK repeat 355..380 CDD:293786
PKc_TNNI3K 522..780 CDD:270966 76/305 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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