DRSC/TRiP Functional Genomics Resources

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Protein Alignment ASH1L and cti6

DIOPT Version :10

Sequence 1:NP_001353106.1 Gene:ASH1L / 55870 HGNCID:19088 Length:2969 Species:Homo sapiens
Sequence 2:NP_595212.1 Gene:cti6 / 2539769 PomBaseID:SPBC1685.08 Length:424 Species:Schizosaccharomyces pombe


Alignment Length:401 Identity:81/401 - (20%)
Similarity:134/401 - (33%) Gaps:173/401 - (43%)


- Green bases have known domain annotations that are detailed below.


Human  2547 RHEASAQIDEIVGETASEADSSET---SVSE-KENGHEKDDDVIRCICGLYK------DEGLMIQ 2601
            :.|.|.:|.:      |..|:..|   |||: :||......:|.||:||:.:      |.||.||
pombe    12 KEEESEKIQK------SPVDTPHTPNGSVSDNEENETSSTGEVTRCVCGIVESDDEASDGGLYIQ 70

Human  2602 CDKCMVWQHCDCMGV--NSDV-EHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLL 2663
            ||:|.||||.:|:|.  .|:| |.|.||.|.|.        ..:.:....|.             
pombe    71 CDQCSVWQHGNCVGFADESEVPEVYYCEICHPE--------FHKVYQRGRGA------------- 114

Human  2664 RQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHET 2728
                     :.|:...:|.|:..|                       :.||          ...|
pombe   115 ---------KQSKYLGNGKPIEAS-----------------------QTEE----------SSST 137

Human  2729 HHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICDYRLDKSAHL 2793
            ..||:.:                                                          
pombe   138 PPSPATK---------------------------------------------------------- 144

Human  2794 FYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPP-------- 2850
              |..:.|..:.::..|.| :.:.|...|:.|  .:|   :|:.||:|.||  ..||        
pombe   145 --KSSKQRLTMNSRDAALD-YEEYLAIAKEKS--LIP---RRSRGRTSSKS--LSPPAPQDESQG 199

Human  2851 ----LKDLGQEDDALPLIEEVLASQEQAANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTC 2911
                ||...:|::     :|:|...:::.:|    .|..:|.:|.||:|.:...||:....:...
pombe   200 TEINLKQKIEEEN-----DEILEDSKESKDE----NEENKETSTTNVAETDAPEEETVDTVEEIA 255

Human  2912 TPEERRHNQRE 2922
              :|.:|:.:|
pombe   256 --DEEKHSVKE 264

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
ASH1LNP_001353106.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..70
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..143
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 501..525
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 537..583
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 824..845
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 878..966
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1100..1128
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1151..1231
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1243..1281
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1489..1508
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1580..1711
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1741..1761
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1911..1991
Catalytic domain 2069..2288
AWS 2092..2143 CDD:197795
SET_ASH1L 2146..2286 CDD:380951
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2288..2346