Protein Alignment kcns3b and Shawl

DIOPT Version :10

• Sequence 1: NP_001032460.1
• Gene: kcns3b / 558674
• ZFINID: ZDB-GENE-051120-78
• Length: 424
• Species: Danio rerio
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 145/551 - (26%)
• Similarity: 232/551 - (42%)
• Gaps: 180/551 - (32%)

Zfish    14 EDLVNLNIGGIHHKVERCVLLRFPHTRVAQLIQCHSDAAILELCDDYSPTEQEYYFDRSPQVFHC 78
            |:.:.||:.||.::..:..|.:.|.||:::|         .|...:|.|...||:|||.|.||..
  Fly     4 ENRIILNVSGIRYETYKATLKKIPATRLSRL---------TEALANYDPVLNEYFFDRHPGVFTQ 59

Zfish    79 VLNFYRTGHFHTLEELCVFCFSQEIEYWGLCELDLDACCLEW--------------FLERKD-EH 128
            :||:||||..|...::|...|.:|:|:|||....::.||  |              .|::.| |:
  Fly    60 ILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCC--WSTYSIHRDTQNTLAILDKLDIEN 122

Zfish   129 ELNSSGQSSK------NASSGEISVTSEDLWKSEGMRCSDVRKLMWETLEDPQHSRCSRGVAAVS 187
            |..:..|.::      ..|:||:     :.|:.       ::..:|...::|..|..::.||.:|
  Fly   123 EKPTEEQIARLFGFEEALSNGEL-----NCWQR-------IKPKIWAMFDEPSSSTGAKIVAGMS 175

Zfish   188 VLVILISILAMCVHSLPEFRY----------------------------QTDGEH---------- 214
            |..|.:|:::.|:.:.|.||.                            ||...|
  Fly   176 VFFIFVSVISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGS 240

Zfish   215 --------------------------------------------SVLDS---------------- 219
                                                        |:|:.
  Fly   241 IGPTFRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHG 305

Zfish   220 --------------VELFCIVFFSVEFFLRVIAAPQPLRFLGNPLNMIDVASILPFYITLAVERL 270
                          |||.|.|:|.:|..:|:|.:|...:|:.:|:|:||..:.|.|| |..::|:
  Fly   306 WIETYGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-TDVMQRM 369

Zfish   271 DEEDKEENQSLVNMGRVVQVLRLMRSFRVLKLARHSEGMRAFGETLMNCQCEVGLLVLFITVGIS 335
            .|        ...:.....::|:||.|   ||.|||.|:|....|......|:.|||.|:.:||.
  Fly   370 GE--------YTGLLEAFSIVRIMRLF---KLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIV 423

Zfish   336 FFSTFIYYTEK--EEASSQLSSIPICWWWGIISMTTVGYGDVYPLTVAGRIVATVCILCGLLVIS 398
            ||::..||.||  :...:|..|||:..||.|::|||||||||.|.|..|..|..:|.|.|:|.|:
  Fly   424 FFASLAYYAEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIA 488

Zfish   399 LPITIIMNNFSKYF----------EKNRKCL 419
            ||:.:|::|||.::          :|.|:.|
  Fly   489 LPVPVIVSNFSMFYSHTQARSKLPKKRRRVL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kcns3b	NP_001032460.1	BTB_POZ	15..117	CDD:453885	34/101 (34%)
		Ion_trans	186..414	CDD:459842	90/351 (26%)
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	38/121 (31%)
		Ion_trans	307..506	CDD:459842	77/210 (37%)