Protein Alignment USE1 and Use1

DIOPT Version :10

• Sequence 1: NP_060937.2
• Gene: USE1 / 55850
• HGNCID: 30882
• Length: 259
• Species: Homo sapiens
• Sequence 2: NP_648289.2
• Gene: Use1 / 39051
• FlyBaseID: FBgn0035965
• Length: 250
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 82/263 - (31%)
• Similarity: 135/263 - (51%)
• Gaps: 21/263 - (7%)

Human     3 ASRLELNLVRLLSRCEAMAAEKRDPDEWRLEKYVGALEDMLQALKVHASKPASEVINEYSWKVDF 67
            |::|.:|:..||:.||.:|  |.:.:.|||:|::.:|:.||..|:......:.:.|..|..:
  Fly     2 ATKLNVNIRTLLANCEELA--KSEQNFWRLQKFIKSLDTMLAELEAMGDPQSVKRIPGYLER--- 61

Human    68 LKGMLQAEKLTSSSEKALANQFLAPGRVPTTARERVPATKTVHLQSRARYTSEMRSELLGTDSAE 132
                |||.|:::.......:....|.:....:.....|.|.:.....::|.:|:|.|||....|
  Fly    62 ----LQALKISTGYADVPGSTTKTPSQSSAVSETGENALKEIRQLQNSKYHNELRKELLQDSDA- 121

Human   133 PEMDVRKRTGV------AGSQPVSEKQLAAELDLVLQRHQNLQEKLAEEMLGLARSLKTNTLAAQ 191
                :|:|.|.      :||..|.|.. ...::...:.:.|.|||:.|.||.|.|:||..|..|.
  Fly   122 ----LRRRRGADESSSSSGSANVQETS-GENMNQAAKYYTNAQEKITEHMLSLTRNLKEQTETAN 181

Human   192 SVIKKDNQTLSHSLKMADQNLEKLKTESERLEQHTQKSVNWLLWAMLIIVCFIFISMILFIRIMP 256
            .:|::|.:.:|.|..|||:|:..|..|:|:||||::|:....||.|:..|...||.|:||::||.
  Fly   182 RIIRRDTEVVSRSAGMADRNINSLGKEAEKLEQHSKKAYKCWLWLMIAFVIATFIGMVLFMKIMK 246

Human   257 KLK 259
            |.|
  Fly   247 KKK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
USE1	NP_060937.2	Use1	5..255	CDD:462882	77/255 (30%)
Use1	NP_648289.2	Use1	4..245	CDD:462882	77/255 (30%)