Protein Alignment PRKCG and Prkcg

DIOPT Version :10

• Sequence 1: NP_001303258.1
• Gene: PRKCG / 5582
• HGNCID: 9402
• Length: 710
• Species: Homo sapiens
• Sequence 2: NP_035232.1
• Gene: Prkcg / 18752
• MGIID: 97597
• Length: 697
• Species: Mus musculus
• Alignment Length: 697
• Identity: 689/697 - (98%)
• Similarity: 694/697 - (99%)
• Gaps: 0/697 - (0%)

Human     1 MAGLGPGVGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQ 65
            |||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQ 65

Human    66 CQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMK 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 CQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMK 130

Human   131 CSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPY 195
            |||||||||||||||||||||||||||||||||||||||:||||:||||||||||||||||||||
Mouse   131 CSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPY 195

Human   196 VKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMS 260
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 VKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMS 260

Human   261 FGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQKFEACNYPLELYERVRMGPSSSPIP 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 FGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQKFEACNYPLELYERVRMGPSSSPIP 325

Human   326 SPSPSPTDPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQD 390
            ||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 SPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQD 390

Human   391 DDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEP 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   391 DDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEP 455

Human   456 HAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPD 520
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||
Mouse   456 HAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPD 520

Human   521 YIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAI 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 YIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAI 585

Human   586 CKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGENFDKFFTRA 650
            ||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||
Mouse   586 CKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSGENFDKFFTRA 650

Human   651 APALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVI 697
            ||||||||||||||||||||||||||||||||||||||||||||||:
Mouse   651 APALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKCG	NP_001303258.1	C1_cPKC_rpt1	34..91	CDD:410383	56/56 (100%)
		C1_cPKC_rpt2	101..154	CDD:410386	52/52 (100%)
		C2_PKC_alpha_gamma	158..289	CDD:175992	127/130 (98%)
		STKc_cPKC	354..677	CDD:270739	320/322 (99%)
Prkcg	NP_035232.1	C1_cPKC_rpt1	34..91	CDD:410383	56/56 (100%)
		C1_cPKC_rpt2	101..154	CDD:410386	52/52 (100%)
		C2_PKC_alpha_gamma	158..289	CDD:175992	127/130 (98%)
		STKc_cPKC	354..677	CDD:270739	320/322 (99%)