Protein Alignment RCOR3 and rcor3

DIOPT Version :10

• Sequence 1: NP_001336998.1
• Gene: RCOR3 / 55758
• HGNCID: 25594
• Length: 585
• Species: Homo sapiens
• Sequence 2: NP_001038494.1
• Gene: rcor3 / 563808
• ZFINID: ZDB-GENE-050208-371
• Length: 547
• Species: Danio rerio
• Alignment Length: 597
• Identity: 418/597 - (70%)
• Similarity: 479/597 - (80%)
• Gaps: 62/597 - (10%)

Human     1 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMRVGAEY 65
            |||||:||.|.|||.|| ||: |||       ::::||  |:|: |||  ||||||||||||::|
Zfish     1 MPGMMDKGSEYLGKGRS-NGT-KSP-------SNASNG--HFSD-ESG--SDDEHDVGMRVGSDY 51

Human    66 QARIPEFDPVETRSCYVSQAGLKLRGSSHPPSLASQSAGIIGATKYTDKDNGGMLVWSPYHSIPD 130
            ||.||||||                                |::||:|||:||||||||:|:|.|
Zfish    52 QANIPEFDP--------------------------------GSSKYSDKDSGGMLVWSPHHTILD 84

Human   131 AKLDEYIAIAKEKHGYNVEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHG 195
            :||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    85 SKLDEYIAIAKEKHGYNVEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHG 149

Human   196 KSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGND 260
            |||||||||||||:|:|||||||||||||||||||||||||||||:||.:|::::||.:|::.||
Zfish   150 KSFHRIQQMLPDKSISSLVKYYYSWKKTRSRTSLMDRQARKLANRNNQDESEEEMEEANPVEAND 214

Human   261 SDYDPKKEAKKEGNTEQPVQT--SKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSC 323
            |||||.||||||.||....||  ||||:|||::|:||||||:||||||||||||||||||||:||
Zfish   215 SDYDPTKEAKKEVNTPAEPQTLSSKIGMGRRDHQTLQHRHHTQRSKCRPPKGMYLTQEDVVAISC 279

Human   324 SPNAANTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLA 388
            |.:|||::||||||||:|||||||||||:||.||||:|.||:|.:.||..|||||||||:|||||
Zfish   280 SSSAANSVLRQLDMELVSLKRQVQNAKQLNSGLKQKIEDGIDELRLPECTQKINARWTTDEQLLA 344

Human   389 VQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEE 453
            |||||||||||||||||||||||||||||||||||||||:||||||||||||:..|||.:..||:
Zfish   345 VQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLDEVLQEWEAEQGTRTPNGDGANSGED 409

Human   454 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPAL 518
            .|: ||..||||||||||  ..|.....||||...||:..|.:..::|.||||||||:|||.|||
Zfish   410 GKT-SNASSGKSTDEEEE--EGQVSLACGPSPVVSSSSSCPPSSSSSLQQPPPLLRPSLPATPAL 471

Human   519 HRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVL--------STVGGQQPPSLIG 575
            |||||||||||||:||||.|:| |||||||:|.:||||||||..        :...|||||:|:|
Zfish   472 HRQPPPLQQQARFLQPRPALHQ-PPPLIRPSNPVPPRLNPRPAAPLAPSTANTPAAGQQPPALLG 535

Human   576 IQT--DSQSSLH 585
            ||:  ...||||
Zfish   536 IQSAETPSSSLH 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RCOR3	NP_001336998.1	ELM2	59..142	CDD:460214	39/82 (48%)
		SANT	178..222	CDD:473887	41/43 (95%)
		Myb_DNA-binding	379..422	CDD:459731	41/42 (98%)
rcor3	NP_001038494.1	ELM2	45..96	CDD:460214	39/82 (48%)
		SANT	132..176	CDD:473887	41/43 (95%)
		Myb_DNA-binding	335..378	CDD:459731	41/42 (98%)
		PHA03247	<467..532	CDD:223021	43/65 (66%)