Protein Alignment OGDHL and CG1544

DIOPT Version :10

• Sequence 1: NP_060715.2
• Gene: OGDHL / 55753
• HGNCID: 25590
• Length: 1010
• Species: Homo sapiens
• Sequence 2: NP_651849.1
• Gene: CG1544 / 43689
• FlyBaseID: FBgn0039827
• Length: 919
• Species: Drosophila melanogaster
• Alignment Length: 970
• Identity: 344/970 - (35%)
• Similarity: 530/970 - (54%)
• Gaps: 121/970 - (12%)

Human    88 PRPPSVVHESRSAV----SSRTKTSKLVEDHLA-------VQSLIRAYQIRGHHVAQLDPLGILD 141
            |||.|..:.|...|    ....:..::.||..|       |...:.|::..||.:|.::|:.|..
  Fly    16 PRPQSRCYHSEKGVWGYKPIAQREFQVAEDVRASRNSQANVYRFVEAFRQHGHKLAAVNPISIRT 80

Human   142 A--DLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTT--FIGGSENTLSLREIIRRLENTYC 202
            :  :|....|          |||.||.       |.|..|  .:.|.:...::.::.:.|::.||
  Fly    81 SQQELQELSP----------AFYGLQT-------QEPVRTDGLLSGPQVAHNVAQLEQLLKDIYC 128

Human   203 -QHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFG 266
             :....||.::.|:|:.:|:.:.|||....|....|:..:...|::|..:::|:|.|:.:.||:|
  Fly   129 GRSTSAEFSYVEDIEEREWLARNFETLDQQQLGKSERCEIAELLIKSQAWDNFMALKFPTVKRYG 193

Human   267 LEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGS 331
            .||.|.|:.....::..|.:..||:|:|.||||||..:.|.::.....::|    .||..|.|.|
  Fly   194 GEGAESMLAFFWQLLRDSVQANIEHVVLAMPHRGRTPLQAALLNMRPAKVF----RKLSGASEFS 254

Human   332 GDVK--------YHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQ-- 386
            .|::        :|:.   |:: ::..:.::.|:|.|||||||.:||..|||:::|..||:..
  Fly   255 EDIEAMSDVISHFHVS---EQL-KILGKKLSFSMVRNPSHLEAANPVAMGKTRSKQQARGEGAFG 315

Human   387 ------GKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSS 445
                  |:.|:::::||||||||||:..|..:::.:|.:...|::|::||||:||||.....||:
  Fly   316 DGSQPFGEHVLNVILHGDAAFAGQGINQECLNMAYVPHFEVGGSLHLIVNNQVGFTTPGDRGRST 380

Human   446 PYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQ 510
            .|.:|:|:.:.||:||||.|||||:..|.|:|..::..|.||:.:||.|:||.||||:|:|.||.
  Fly   381 AYTSDLAKSIQAPVFHVNGDDPEALARVTSLAFRYQREFRKDIFIDLNCFRRWGHNELDDPTFTN 445

Human   511 PLMYKQIHRQVPVLKKYADKLIAEGTVT---LQEFEEEIAKYDRICEE-----AYGRSKDKKILH 567
            ||:||.:|::..|...||.:|..|..::   .:|..:|..||  :.||     ||
  Fly   446 PLVYKIVHQRESVPDLYAQQLAKEQVLSESKAKEMRDEYMKY--LGEELALAPAY---------- 498

Human   568 IKHWLDSPWPGFF-----NVDGEP-KSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRI- 625
                  .|.|.:|     |....| |.:|...||:...:|.:||..:.:.| |||.||..|.:.
  Fly   499 ------QPPPSYFEKQWTNFQLAPSKELTYWDTGLDYSLLHYIGQQSVTFP-EDFNIHPHLLKTH 556

Human   626 LRGRADMTKNRT-VDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 689
            :..|....:|.. :||:.||.:|.|||:.:|.:||:||:||.||||||||.:|.||:.: ...:|
  Fly   557 VNARLKKLENGVKIDWSTAEALAIGSLMYQGHNVRISGEDVGRGTFSHRHAMLVDQQTN-EMFIP 620

Human   690 MNHL-WPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQ 753
            :|.: ..:.....:.:|.|||..|||||.|.|:.:||.|::||||||||.|.||.|||.||.:|:
  Fly   621 LNSMEGGNGGKLELAHSILSEEAVLGFEYGMAIDNPNNLIIWEAQFGDFANGAQIIIDTFIVSGE 685

Human   754 AKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQM-----SNDDSDAYPAFTKDFEVSQLYDCNW 813
            .||:..|.:|:|||||.:|...||||.|.|||||:     ::.|.|:               .|.
  Fly   686 TKWMESNALVMLLPHGYDGAASEHSSCRIERFLQLCDSKETSADGDS---------------VNV 735

Human   814 IVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAA 878
            .:||.:|||.|:||||||:...|||||::..||:|||.|.|.|:.:....||.|..|:   |...
  Fly   736 HIVNPTTPAQYYHVLRRQLARNFRKPLVVVAPKTLLRLPAATSTHEDFQPGTLFHNVL---GDTI 797

Human   879 RAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAE-LAWC 942
            ..||||:::|.|:||.||.|.:||..:...: .||.|||.:.|||...::.:..:|...: ..|.
  Fly   798 AKPEQVRKVILCSGKHYYTLAEEREKRQAYD-TAILRLESLCPFPIQELQAQLAQYGNVQSFVWS 861

Human   943 QEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNL 1002
            ||||:|||.:.::.|||..::  .:.:.|.||..|..||||....|...:.:.:...|.|
  Fly   862 QEEHRNMGAWTFVRPRFENLI--GQQLHYCGRCEAPTPATGIGKVHKREVDEIVAAPFEL 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OGDHL	NP_060715.2	SucA	51..1002	CDD:440333	343/968 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..100		5/11 (45%)
CG1544	NP_651849.1	SucA	36..919	CDD:440333	337/948 (36%)